ABSTRACT
Holigarna grahamii (Wight) Kurz. is large tree belonging to family anacardiaceae. The bark is smooth and gray in colour, leaves are simple, alternate, glabrous, and midrib is flat. Medicinal plants contribute in human health care system. Most of the plants utilized by village peoples as a folk medicine. Antibacterial activity of the leaves and bark extracts of Holigarna grahamii (Wight) Kurz. against pathogenic bacteria like gram positive (Bacillus subtilis, Staphylococcus aureus) and gram negative (Escherichia coli and Salmonella typhi, Proteus vulgaris) bacteria by in vitro agar well diffusion method. The maximum zone of inhibition of bark extract is observed in Staphylococcus aureus (8.331.15) while in leaves extract it is observed in Escherichia coli (2.660.57). The phytochemical screening of leaf and bark extract shows presence of phenols, tannins, alkaloids and reducing sugar.
ABSTRACT
PURPOSE: The purpose of study was to compare blood glucose in capillary finger-prick blood and gingival crevice blood using a self-monitoring blood glucose device among patients with gingivitis or periodontitis. METHODS: Thirty patients with gingivitis or periodontitis and bleeding on probing (BOP) were chosen. The following clinical periodontal parameters were noted: probing depth, BOP, gingival bleeding index, and periodontal disease index. Blood samples were collected from gingival crevicular blood (GCB) and capillary finger-prick blood (CFB). These samples were analyzed using a glucose self-monitoring device. RESULTS: Descriptive statistical analysis has been carried out in the present study. Data were analyzed using a Pearson's correlation coefficient and Student's t-test. A r-value of 0.97 shows very strong correlation between CFB and GCB, which was statistically highly significant (P<0.0001). CONCLUSIONS: The authors conclude that GCB may serve as potential source of screening blood glucose during routine periodontal examination in populations with an unknown history of diabetes mellitus.