ABSTRACT
Hypercholesterolaemia is the state been depicted by an expanded greasy substances called lipids, rise in plasma TCs and TGs levels it is additionally called hyper lipoproteinemia. The present study was designed to investigate the hypolipidemic effect of ethanolic extract of Crossandra infundibuliformis leaves and stem (ECILS) in high fat diet (cholesterol 2%, sodium cholate 1%, sucrose 48%, peanut oil, methionine 4%, and 47% normal laboratory feed) . The rats feed with High-fat diet containing (cholesterol 2%, sodium cholate 1%, sucrose 48%, peanut oil, methionine 4%, and 47% normal standard laboratory feed) for 1 month, and then they are checked for the blood parameter levels like TC, TGs, LDL, VLDL, and HDL. Ethanolic extracts at low dose (100 mg/kg), significantly reduced the levels of TC, TGL, LDL, VLDL & increased the levels of HDL and reduced the body weights on 30st day, and at medium, high doses it reduced the levels of TC, TGL, LDL, VLDL & increased the levels of HDL and reduced the body weights.
ABSTRACT
Background: Refractive errors are one of the known cause of visual impairment and a main cause of blindness worldwide. In children, refractive errors make us learning disabilities and also prevent academic progression. Aim: To study the prevalence of refractive errors in children of school going age. Materials and methods: This was a descriptive study in which children were screened for refractive errors. Children aged 4 to 15 years whose parents were willing to sign the informed consent form. This study was done from 2011 to 2015. Results: Total 531121 children were screened in which 13206 having refractive errors, incidence of 2.4% in the present local area. The most common age group affected is 8-11 years of these were boys 2706 (20.4%) and 3491 (26.4%) girls. Conclusion: The major cause of visual impairment worldwide is refractive errors and have immediate and long term consequences in children.