ABSTRACT
Abstract Lymphocytic thrombophilic arteritis is a recently described entity, histopathologically characterized by lymphocytic vasculitis that affects the arterioles of the dermo-hypodermic junction, associated with deposition of fibrin and a luminal fibrin ring. A 49-year-old female patient presented with achromic maculae and a well-defined ulcer on the medial aspect of the left lower limb. The biopsy showed intense inflammatory infiltrate in the papillary dermis with a predominance of lymphocytes, and medium-caliber vessels surrounded by mononuclear infiltrates in the deep reticular dermis. Masson's trichrome staining showed intense destruction of the muscle layer of the vascular wall and a fibrin ring. Good clinical response was attained with azathioprine. The authors believe that the ulceration might be another clinical presentation or represent an atypical progression of this condition.
Subject(s)
Humans , Female , Arteritis , Leg Ulcer/etiology , Ulcer , Biopsy , Lymphocytes , Middle AgedABSTRACT
Abstract: Lupus erythemathosus is a chronic, relapsing disease with acute, subacute, and chronic lesions. Effluvium telogen occurs in the setting of systemic activity of the disease, and cicatricial alopecia results from discoid lesionsin on the scalp. Other types of alopecia, like alopecia areata, may rarely be found in lupus. Frontal fibrosing alopecia is characterized by frontotemporal hairline recession and eybrow loss. Histophatologically, it cannot be differentiated from lichen planopilaris.It is controversial whether frontal fibrosing alopecia is a subtype of lichen planopilaris.. A pacient with chronic lichenoid lupus erythematosus is described with clinical, histophatological and dermoscopic features of frontal fibrosing alopecia.We have not been able to find in the literature cases of frontal fibrosing alopecia as a clinical manifestation of lupus.
Subject(s)
Humans , Female , Middle Aged , Lupus Erythematosus, Discoid/complications , Lupus Erythematosus, Discoid/pathology , Alopecia/complications , Alopecia/pathology , Scalp/pathology , Biopsy , Fibrosis/pathology , Lichenoid Eruptions/pathology , DermoscopySubject(s)
Humans , Female , Adult , Biological Therapy/adverse effects , Pemphigus/chemically induced , Drug Eruptions/etiology , Antibodies, Monoclonal/adverse effects , Arthritis, Rheumatoid/drug therapy , Skin/pathology , Immunohistochemistry , Pemphigus/pathology , Drug Eruptions/pathology , Erythema/chemically induced , Erythema/pathology , Antibodies, Monoclonal, HumanizedABSTRACT
Infantile digital fibromatosis or Reye's tumor is a benign fibroproliferative tumor, the etiopathogenesis of which has yet to be fully clarified. It typically presents at birth or in the first year of life and is characterized by a firm, flesh colored or erythematous nodule or nodules located on the digits. These lesions tend to regress spontaneously.
A fibromatose digital infantil ou tumor de Reye é um tumor fibroso benigno de etiologia desconhecida, presente ao nascimento ou com aparecimento no primeiro ano de vida. Caracteriza-se por nódulos firmes, únicos ou múltiplos, normocrômicos ou eritematosos, localizados nas falanges, com tendência à regressão espontânea.