ABSTRACT
@#<p><strong>OBJECTIVE:</strong> To present a case of carcinoma ex pleomorphic adenoma in the parapharyngeal space and discuss its management.<br /><br /><strong>METHODS:</strong> <br /><strong>Design:</strong> Case Report<br /><strong>Setting:</strong> Tertiary Government Teaching Hospital<br /><strong>Patient:</strong> One<br /><br /><strong>RESULTS:</strong> A 40-year-old male patient with dysphagia for three months and a left-sided mucosa-covered oropharyngeal mass was found to have a prestyloid parapharyngeal lesion on CT scans. Fine Needle Aspiration Cytology (FNAC) revealed a pleomorphic adenoma. With a past history of parapharyngeal pleomorphic adenoma excised transorally three years before, the present mass was excised by mandibular swing approach. Post-operative recovery was uneventful but the final histopathological report was carcinoma ex pleomorphic adenoma. <br /><br /><strong>CONCLUSION:</strong> Malignant transformation should be suspected in recurrent salivary tumors in the parapharyngeal space. Provided there was truly no pre-existing malignant focus in the originally-excised tumor, and that early recurrence was not due to inadequate initial excision, this patient had a rare condition where the same tumor underwent malignant transformation within three years only. To the best of our knowledge, such an early transformation to malignancy of a minor salivary gland tumor of the parapharyngeal space has not been reported in the English literature.</p>
Subject(s)
Humans , Male , Carcinoma , AdenomaABSTRACT
To present a retrospective case series of Sino-nasal malignant melanoma cases consisting of eight cases, their clinical presentation, management protocol and treatment outcome.: Retrospective review of 8 sino-nasal melanoma patients with their clinical profile, investigation result and treatment outcome with comprehensive review of literature. The 5-year survival rate in this small series was nil. Local failure with skull base invasion was noticed in 3 cases. Distant metastasis was noticed in 4 cases. Advanced sino nasal malignant melanoma carries a poor prognosis as seen in the present series. Early diagnosis and adequate surgical excision is beneficial in managing these lesions
ABSTRACT
Developmental anomalies of the nose encompass a diverse group of conditions. Embryologic development anomalies of the nose include nasal dermoids, gliomas, encephaloceles, nasal clefts, proboscis lateralis, arhinia, polyrrhinia, nasopharyngeal teratoma, and epignathus. Supernumerary nostril is a very rare congenital anomaly. We report such a case with review of literature. Embryology of nasal development and embryogenesis of duplication anomalies are discussed in this review
ABSTRACT
A retrospective longitudinal study was conducted on 166 patients of clinically evident salivary gland tumours over a period of l0years with the main aim to assess the prognosis of the various surgical techniques used in the management of salivary gland tumours. All the patients underwent detailed clinical examination and FNAC. CECT and MR scan were done whenever indicated. After meticulous assessment of the extent and establishment of the cytopathological diagnosis, these cases underwent surgical excision of the tumour. Various surgical approaches were described for the excision of the tumours of various size, type and extension, with or without nodal metastasis. Neck dissection was done in 54% cases of salivary gland malignancies. Excisional biopsy was done in all of the cases. Post-operative radiotherapy was given in 26% cases. 6% cases of malignant salivary gland tumours showed recurrence