ABSTRACT
Introduction: Misdiagnosis of histologic type on frozensection could result in incomplete surgical staging of a moreaggressive ovarian cancer, ultimately leading to an inabilityto prognosticate, inappropriate treatment, need for repeatsurgery, and decreased survival. Study aimed to investigatethe discordance rate of the frozen section with final pathologyin the diagnosis of mucinous histology in ovarian tumors.Material and Methods: In this retrospective study cases ofmucinous ovarian tumor on frozen section or final pathologywere included from 2012 to 2018. Cases reporting a mucinousthe ovarian tumor on frozen section or final pathology wereidentified. Frozen section results were compared with finaldiagnosis to calculate concordance rates.Results: Of the 38 cases reported to be mucinous on frozensection, 36 had mucinous histology confirmed on finalpathology (94.7% concordance). Among the 36 mucinoustumors found to be concordant in mucinous histologic type onfrozen section and final pathology, there was a 61.1% (22/36)concordance rate on the classification of malignancy. Lymphnode dissection was performed in 12 of the 38 cases reportedto be mucinous on frozen section.Conclusion: All of these distinctions provide significantevidence that mucinous ovarian tumors should be approachedsurgically as a distinct entity
ABSTRACT
Introduction: Optimal therapy for patients with metastatic neck disease remains controversial. Neck dissection followingradiotherapy has, traditionally, been used to improve locoregional control.Aim: The aim of the study was to study the neck dissection in post-RT clinically negative neck (cN0) in advanced T3/T4 oralmalignancies.Materials and Methods: In this retrospective study, cases of oral squamous cell carcinoma were included from 2014 to 2018.The study includes 16 patients with a cN0. Patients with advanced T stage (T3/T4), the presence of lymphovascular invasion,the presence of perineural invasion, positive surgical margins, lymph node involvement, extracapsular nodal extension, andbone involvement were received post-operative radiotherapy (PORT).Results: A total of 16 cases were included in the study, the PORT was given to six patients where three of them were pN+and three were pN0 but had adverse features of primary tumors that mandate PORT. The regional recurrence had occurredin 1 case which was pN+.Conclusion: Tumor recurrence was not influenced statistically with the use of PORT in the cN0.
ABSTRACT
Aim The aim of this study was to review and describe techniques for the reconstruction of defects after resection of lip squamous cell carcinoma with emphasis on cosmetic and functional outcome. Patients and Methods A review of techniques and selected case presentations using different flap designs for the reconstruction of perioral defects following resection of squamous cell carcinoma in 25 patients out of 128 cases of head and neck malignancies was performed in period of 2017-2018 in Regional Cancer Centre,Govt Coimbatore medical college hospital. The Abbe estlander ,Nasolabial flap,Karapandzic flaps5 deltopectoral ,PMMF flap were used for lip defects. Results All reconstructed patients had acceptable functional results and healed without complication. Seven tumors were located in upper lip, Eight tumors in lower lip and Ten tumors in the angle of mouth. The lip defects were easily closed with the Karapandzic flaps, Abbe estlander ,nasolabial ,deltopectoral flap, forehead flap. While cosmesis was acceptable in all cases, the commissure was the most difficult region to reconstruct with a esthetic appearance and functional outcome. There were no flap failures.Oral competence was noted to be better in Karapandzic flaps, Abbe estlander flap,Nasolabial flap than deltopectoral/ forehead flap. Conclusion The Karapandzic,nasolabial and Abbe estlander flaps provide a easy and useful method to reconstruct perioral defects following resection for oral cancer.