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Background: Diabetes Mellitus refers to a group of common metabolic disorders that share the phenotype of Hyperglycemia. It is the leading cause of morbidity and mortality throughout the world with an estimated worldwide prevalence of 439 million by 2030 and 19% of world抯 DM patients are Indians. Magnesium is an important co-factor for various enzymes involved in Insulin secretion and is involved in sodium-potassium ATPase pump. 25%-38% of Type 2 DM patients had Hypomagnesemia, which has also contributed in developing microvascular complications such as Diabetic Retinopathy (DR) and Diabetic Nephropathy (DN). Various studies have suggested that Magnesium supplementation in Type 2 DM patients with Hypomagnesemia have shown beneficial effects on insulin sensitivity and glucose metabolism. Aim and objectives: To study the prevalence of Hypomagnesemia in Type 2 DM patients and to study the association of Hypomagnesemia with microvascular complications such as DR and DN. Materials and methods: It is a hospital based Observational study carried out in 2022 for a period of 1 year including 60 patients fulfilling the ADA criteria for diagnosing T2DM and patients with Diabetic Retinopathy and Diabetic Nephropathy, and excluding patients with Malabsorption, Chronic diarrhoea, Renal Failure on diuretic therapy, Sepsis, Pancreatitis. Serum Magnesium levels of 1.6 mg/dl � 2.6 mg/dl is considered as normal range. Serum Magnesium were measured using Xylidyl blue colorimetric method. Results: The Mean age of the patients in our study was 55.89 years. Among 60 patients diagnosed with Diabetes Mellitus, 42 patients had Hypomagnesemia, 18 patients had Normomagnesemia (p- value: <0.0001). Patients with an HbA1c levels > 7% had Hypomagnesemia when to compared to patients with HbA1c <7% with a significant p value of 0.009. Hypomagnesemia was also associated with Diabetic Retinopathy and Diabetic Nephropathy with a significant p-value of 0.013 and 0.009 respectively. Conclusion: In our study, it has shown that patients with uncontrolled T2DM had Hypomagnesemia, which is also associated with micro-vascular complications of T2DM such as DR and DN.
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Superior Vena Cava Syndrome is the clinical manifestation of the Superior Vena Cava obstruction, with severe reduction in venous return from the head, neck and upper extremities. More than 80% cases of SVCS is nearly attributable to advanced malignancy, most commonly lung cancer. SVC syndrome is characterized by congestion and swelling of the face and upper thorax, with distended superficial chest veins. The most severe complications of SVC syndrome include Glottic edema and venous thrombosis in the central nervous system. We represent a case SVC syndrome due to Small Cell Cancer of the lung.
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Objective: To compare outcomes of preterm neonates born through assisted reproduction techniques (ART) and non-ART conception. Methods: This retrospective cohort study included very preterm neonates (26 weeks to 31 weeks) admitted to our neonatal unit over a six year period from 2014 to 2019. The primary outcome was composite adverse outcome of mortality or any of the major morbidities i.e., intraventricular hemorrhage (IVH) grade ?3, periventricular leukomalacia (PVL) grade ?2, bronchopulmonary dysplasia (BPD) at 36 weeks, and retinopathy of prematurity (ROP) requiring treatment. Results: Total of 759 neonates (253 in ART group, 506 in non-ART group) were included after propensity score matching for gestational age, sex, and small for gestational age (SGA). Neonates in ART group had similar rates of composite adverse outcome [aOR (95% CI) 0.86 (0.55 – 1.36)], mortality [0.93, (0.53- 1.64)] BPD [1.18, (0.37 – 3.76)]; ROP requiring treatment [ 0.49 (0.14-1.71], and other morbidities. Conclusion: Very preterm neonates born through ART were not at increased risk of adverse neonatal outcomes.
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Background:COVID-19 pandemic has strained the health infrastructure globally, hence the importance of cost-effective biomarkers. We aimed to identify simple haematological prognostic markers in hospitalized COVID-19 patients to differentiate between milder and severe cases, thus predicting outcome.Methods:A retrospective study of COVID-19 patients admitted at MallaReddy institute of medical sciences was conducted from April to June 2021. Total leukocyte count (TLC), neutrophil-to-lymphocyte ratio (NLR), derived NLR ratio (dNLR) and platelet-to-lymphocyte ratio (PLR) were calculated and correlated with outcome. These parameters were compared with other inflammatory markers using ROC(receiver operator curve)analysis.Results:303 patients of 397 fulfilled the inclusion criteria (male-198, female-105). There was a significant higher mean of NLR in patients with death (14.46�84) compared to patients recovered (8.43�33), similarly the dNLR was higher in death (8.06�34) compared to recovered (4.97�49). A significant positive strength of association between the NLR and dNLR with the ESR, CRP, CORADS score and CT severity score in the patients. The ROC analysis showed the NLR (AUC=0.777) and dNLR (0.799) a better marker to predict the outcome.Conclusions:In COVID-19, immuno-haematological markers like NLR, dNLR, PLR found to be a simple and cost-effective tool to prognosticate the clinical outcome among hospitalized patients and were in concordance with the other inflammatory markers. Hence, these markers serve as better indicators in risk stratification and better management.
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Wound healing is type of tissue repair involving number of processes. These processes influenced by both systemic factors and local factors. Nutrition, metabolic status, circulatory status, hormone levels are the main systemic factors which influence wound healing. In addition to these, infection, mechanical factors, foreign bodies, size, location and type of wound are also influence the wound healing process. Various kinds of complications are occurred when wound is not properly healed. In Ayurveda, the term Vrana is equated to wound of modern parlance and the drugs having both Vranashodhana (wound cleansing) and Vranaropana (wound healing) properties play an important role in wound management. Considering this, single and compound formulations having Vranashodhana and Vranaropana properties are compiled from classical texts and compendia. Clinical trials on wound management through are Ayurvedic drugs/regimen reviewed and presented.
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Introduction: Supracondylar fractures of Humerus are one of the most common fractures in pediatric age group. The aim ofthe study was to evaluate the functional results in the management of supracondylar fracture of humerus in children by variousmethods.Materials and Methods: This study was conducted at the Orthopaedics department of Mahatma Gandhi MemorialHospital, Warangal. This was a 2 years prospective, longitudinal, hospital based, observational study and its outcomes.Participants were a total of 30 children aged 0 to 14 years (21 males, 9 females) diagnosed with supracondylar fractureof humerus.Results: Patients were assessed by Flynn’s criteria. Results were excellent in 70%, good in 20%, fair in 6.66%, and poor in 3.33%.Conclusion: Closed reduction and external immobilization are reserved for Gartland’s type 1 and select type 2 fractures. Inunstable type 2 and type 3, closed or open reduction and K-wire fixation give better results.
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Background: Anemia is a serious public health problem as harmful as the epidemic of infectious disease, especially in developing countries like India. With both the problems occurring together in an individual, the development of complications due to diabetes is severe and much earlier. Aim of the study: To estimate the prevalence of anemia in persons with type 2 diabetes mellitus and its role as a risk factor for the presence and the severity of diabetic retinopathy, in a population-based study. Materials and methods: This was a cross-sectional study conducted in about 200 diabetic inpatients in Government Royapettah Hospital, Chennai over a period of 6 months to study the correlation between low hemoglobin and development of diabetic retinopathy. Results: Fundus examination in anemic group showed normal interpretation in 49 patients, NPDR in 40 patients and 11 had PDR. In the non-anemic group, 68 patients had normal fundus examination, 26 had NPDR and 6 had PDR. The number of patients having diabetic retinopathy was greater in the anemic group than in the non-anemic group. Conclusion: Thus this study showed a positive correlation between anemia and earlier development of diabetic retinopathy. Hence, treatment of anemia must also be considered as a routine entity at the time of diagnosis of diabetes mellitus.
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Background: Knee osteoarthritis is the occurrence of osteoarthritis (OA) in the knee joint. Osteoarthritis involves the degradation of joints, including articular cartilage and subchondral bone. Osteoarthritis is the most common disease of joints adults suffer from worldwide. The most common procedures done for the treatment of osteoarthritis of knee is a surgical procedure called Total knee arthroplasty (TKA) or total knee replacement (TKR) which is mostly done in advance cases. It is usually starts from age group of 40 and slowly progresses. The most common age group in which its seen is between 50-60 years. They slowly start losing balance after the TKR. Balance is an important aspect of mobility and physical function. Patients with severe OA who are awaiting total hip arthroplasty (THA) or total knee arthroplasty (TKA) are reported to have a higher incidence of falls compared to the general population. Balance Training Exercises with Conventional Therapy gives much better effect. So, the aim of the study is to check the effectiveness of balance training to improve function in patients in post-operative phase following total knee arthroplasty. Materials and methods: 60 patients were included in the study which was divided into two groups; Group A and Group B, 30 patients in each group. Subjects were randomly selected and assigned to each group. Pre-test measurements of the patient were done with the help of TUG for each group. The Sreenivasu Kotagiri, Neeti Mathur, Swapna, I Venkateshwarlu, Anup Kumar Songa. Effectiveness of balance training to improve function in patients in post-operative phase following total knee arthroplasty. IAIM, 2019; 6(10): 56-63. Page 57 Subjects in Group-A were given Conventional Therapy. The Subjects in Group-B were given Balance Training Exercises with Conventional Therapy. Then the Result analysis was done. Results: On comparing Group A and Group B for post-treatment TUG score, results showed a significant difference (p=0.001). The overall study proved that Balance Training Exercises with Conventional Therapy is beneficial in improving functional activities and decreasing the disability level. Conclusion: The analysis obtained indicated that Group B (Balance Training Exercises with Conventional Therapy) showed more significant improvement when compared to Group A (Conventional therapy).
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Psoriasis is one of the commonest skin disorders seen in routine clinical scenario, in entire world around 80 million people suffering from psoriasis. Psoriasis is differentiated by patches of abnormal skin. These skin patches are typically red, itchy, and scaly. Psoriasis varies in severity from small, localized patches to complete body coverage. It typically presents as red patches with white scales on top. Areas of the body most commonly affected are the back of the forearms, chin, navel area, and scalp. Diagnosis is typically based on the signs and symptoms. Men and women are affected with equal frequency. The disease may begin at any age, but typically starts in adulthood. Psoriasis is associated with an increased risk of psoriatic arthritis, lymphomas, cardiovascular disease and depression. Psoriatic arthritis affects up to 30 percent of individuals with Psoriasis. It is noted that around 2% of population are touching with Psoriasis. In present study review on Herbs frequently used in treating psoriasis were compiled. The Herbs Nimba, Stri Kutaja, Guduchi, Daruharidra, Bhallataka Haritaki, Aragvadha, Amalaki, Karveera, Saptaparna, Khadira, Vasa, Guggulu, Chitraka & Katuki are reviewed to be having Vata or Kapha balancing properties. The pharmacological studies showing that Nimbidin of Neem having anti psoriatic property, The Methanolic and ethanolic extracts of Stri Kutaja and Guduchi are having anti oxidant and anti psychotic properties which are helpful in reducing the symptoms of psoriasis.
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Background: General inhalational anaesthesia associated with adjuvant intravenous agents provides better sedation, hypnosis and analgesia. Drugs with such effects already established in the literature include benzodiazepines and opioids. Aim: Aim of the study was to evaluate the effect of continuous infusion of Dexmedetomidine, on Sevoflurane requirement during general anesthesia with continuous monitoring of depth of anesthesia by BIS (Bispectral index) analysis in patients undergoing elective laparoscopic surgeries. Materials and methods: 60 patients with ASA grade I and II, aged between 35-55 years, submitted to elective laparoscopic cholecystectomies under General Anesthesia were randomly divided into two groups of 30 each, one group received a loading dose of Dexmedetomidine at 1 mcg/kg for 10 min (10 minutes before starting the surgery), followed by maintenance dose of 0.5 mcg/kg/hour, till the end of surgery. The other group received similar volume of IV Normal Saline. MAP, HR, SpO2, EtCO2 and BIS were evaluated. Results: There was no significant difference (p>0.05) between Dexmed and Saline groups with respect to mean age, weight, height, duration of anaesthesia and ASA grade. There was no significant difference (p>0.05) in the baseline heart rates and baseline mean arterial pressure between the two groups. There was a clinically and statistically significant reduction in HR and MAP in the Dexmed Nitesh Kabra, Nama Nagarjuna Chakravarthy, G. Venkateshwarlu. A bispectral index guided study on the effect of dexmedetomidine on sevoflurane requirements during elective laparoscopic surgeries. IAIM, 2018; 5(7): 67-80. Page 68 group throughout intraoperative period compared to Saline group (p <0.05). There was a statistically significant rise in HR and MAP in the Saline group during laryngoscopy and 15 minutes after the creation of pneumoperitoneum (p<0.05). Dexmed group had a stable hemodynamics during laryngoscopy and creation of pneumoperitoneum. No statistically significant difference was noted in the extubation time of both the groups. Mean RAMSAY Sedation score and Modified ALDRETE score was higher in Dexmed group. Usage of Sevoflurane (in ml) and usage of Sevoflurane /min was significantly low in Dexmed group. Conclusion: Dexmedetomidine as a preanesthetic medication and intraoperative infusion was effective in blunting stress response to laryngoscopy and creation of pneumoperitoneum. It also decreased intraoperative anaesthetic requirement and had significant anaesthetic sparing property during BIS guided general anaesthesia providing a lighter sedation without the prolongation of extubation time or without any significant adverse effects.
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Background: Epidural opioids have unique advantages over conventional, intermittent IV/ IM administration, in that patients given epidural opioids have fewer respiratory complications and can be mobilized sooner in the postoperative period. Aim: To compare the effects of epidural 0.5%Bupivacaine with nalbuphine and 0.5% bupivacaine with fentanyl in lower abdominal and lower limb surgeries. Materials and methods: This prospective, randomized, single blind study, where in Epidural Nalbuphine (10 mg) with 0.5% bupivacaine and epidural fentanyl (50 g) with 0.5% bupivacaine in lower abdominal and lower limb surgeries. Results: There were statistically no significant difference between mean age, weight, gender, ASA grading, types of surgeries and baseline parameters in both groups. The duration of surgery and time of onset of sensory blockade, motor blockade and peak motor blockade were not statistically significant (p> 0.05). The duration of sensory blockade was highly significant (p < 0.01). Duration of motor blockade was not statistically significant (p > 0.05). Mean heart rates in both the groups were significant only at 6th, 7th, 8th, 9th and 10th hours. Mean arterial pressures in both the groups were significant only at 3rd, 6th, 7th, 8th, 9th and 10th hours. 30% of patients in group A had a pain score more than 4 during 6-12 hours of postoperative period as compared to 80% in group B. The pain scores were similar in both the groups in the first six hours of postoperative period. Number of rescue Nama Nagarjuna Chakravarthy, A Sagar, G. Venkateshwarlu. A comparative study of epidural 0.5% bupivacaine with nalbuphine and 0.5% bupivacaine with fentanyl in lower abdominal and lower limb surgeries. IAIM, 2018; 5(2): 124-134. Page 125 analgesics required in the first 24 hours of post-operative period in group B were significantly higher (p < 0.01) when compared with group A. 4 patients (13.2%) in Group B experienced respiratory depression which is significant statistically. Conclusions: Epidural Nalbuphine with 0.5%bupivacaine significantly prolongs the total duration of sensory blockade with better postoperative analgesia when compared to epidural fentanyl with 0.5%bupivacaine, with stable hemodynamics and less side effects.
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Introduction: Laparoscopic surgery is a routinely performed surgery and it is desirable to have stable intra-operative hemodynamic states by avoiding hypertension and tachycardia. Various drugs have been employed to attenuate this hemodynamic response. No single drug is satisfactory. Thus there is a need to find a simple efficient and reliably consistent method. Aim: The present study was undertaken to evaluate the comparison of Dexmedetomidine and Esmolol on perioperative hemodynamic response during laparoscopic cholecystectomy. Materials and methods: Prospective, randomized, controlled, single blinded trial comparing dexmedetomidine (alpha 2- agonist) and esmolol (beta 1-antagonist) done by allocating into two groups. It was conducted in 60 patients of both sex, belong to ASA I and ASA II of age group 20-60 years admitted for laparoscopic surgery from 2016-2017. They were randomly divided into two groups of 30 patients each. The Heart rate (HR), Systolic blood pressure (SBP), Diastolic blood pressure (DBP), Mean arterial pressure (MAP) were recorded prior to induction, after the induction, after the intubation, 15 min, 30 min, 45 min, 60 min after creation of pneumoperitoneum, post pneumoperitoneum, after extubation. Results: Heart rate and systolic blood pressure were significantly lower in Group A after induction, after intubation, and maintained throughout intraoperative and postoperative period compared to Maskuri Soujanya, Nama Nagarjuna Chakravarthy, G. Venkateshwarlu. A study to compare the efficacy of dexmedetomidine with esmolol on hemodynamic response during laparoscopic cholecystectomy. IAIM, 2018; 5(8): 17-29. Page 18 Group B. Diastolic blood pressure were significantly lower in Group A after intubation, and maintained throughout intraoperative period and at extubation compared to Group B. Diastolic blood pressure was not significant after induction, at postoperative period. Mean blood pressure were significantly lower in Group A after induction, after intubation, and maintained throughout intraoperative period and at extubation compared to Group B. Mean blood pressure were not significant at postoperative period. Conclusion: Dexmedetomidine is more effective agent than esmolol in maintaining stable hemodynamics during and after pneumoperitoneum in laparoscopic cholecystectomy.
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Vigna radiata (Fabaceae) is an important pulse crop widespread throughout the tropics and warm temperature regions. In this study, we evaluated the in vitro anti-inflammatory and in vivo antiarthritic activity of Vigna radiata sprouts in rats. The in vitro anti-inflammatory activity was determined by membrane stabilization and protein denaturation method. Whereas, the antiarthritic activity of the ethanolic extract of the sprouts was evaluated by complete Freund’s adjuvant model with diclofenac sodium as the standard drug. Body weights, paw volume, biochemical parameters such as lipid peroxidation, total reduced glutathione, myeloperoxidase and lysosomal enzymes like cathepsin-D, N-acetyl β-D-glucosamindase and β-D-glucuronidase were estimated. Treatment with ethanolic extract of V. radiata exhibited significant membrane stabilization activity and protein denaturation activity, and significantly attenuated the biochemical changes induced by administration of complete Freund’s adjuvant. The findings of the present study suggest the possible role of Vigna radiata in the therapeutics of arthritis.
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Background: Recently much of attention is focused on the diastolic function of the heart. Since the systolic performance of the heart in hypertensive patients has been examined so far, but the study of the diastolic function of heart has emerged as a newer mode of study. Aim: To study non-invasively the diastolic function of left ventricle in patients with systemic hypertension. Materials and methods: Twenty patients either admitted or as outpatients in outpatients Department, Gandhi Hospital with isolated systemic hypertension. (HTN) who satisfied inclusion and exclusion criteria were taken up for the study with five age matched individuals who along served as controls assessed by Doppler Echo-cardiography and their findings were compared with five normotensive age matched controls. Results: Bedside post valsalva maneuver, this test was positive in 7 5% of the test subjects. Of the 25% who had a negative test, 40% had evidence of diastolic dysfunction as assessed by pulsed wave Doppler. Left ventricular hypertrophy was present in 55% of the patient subgroup and all (100%) of these patients had significant diastolic dysfunction. The rest of the 45% of the patients did not have left ventricular hypertrophy. 75% of these non-hypertrophic hypertensives had diastolic dysfunction as seen by PWD. Increased left ventricular mass index has been observed in 85% of the hypertensives but has not correlated statistically with either severity of blood pressure or diastolic filling variables or isovolumic relaxation time. The left atrial size an indirect indicator of LV diastolic function was increased in 50% of the hypertensive subjects when compared with the controls but the statistical C. Venkateshwarlu, B. Praveen Kumar, Md. Yousuf Khan. Evaluation of left ventricular diastolic function in hypertensives. IAIM, 2016; 3(10): 212-220. Page 213 difference was insignificant. LV diastolic function as assessed by PWD mitral flow velocity profile and isometric volume relaxation time was abnormal in 85% of the hypertensive subgroup and was highly significant statistically (P value <0.005). The deceleration time (MS) was similar in both the controls and the hypertensives making it an insignificant parameter for assessing LV diastolic function. The peak filling rate was reduced in the hypertensive subgroup and was of moderate statistical significance. Conclusion: Doppler Echocardiography, an easily available non invasive technique today, can be utilized for identifying hypertensives with diastolic dysfunction and thus treat this group with specific therapy (Beta Blockers) so as to arrest or reverse the pathological changes produced in left ventricle due to hypertension.
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Background: Catheter-associated urinary tract infections (CAUTIs) are the most common hospital acquired infections and a leading cause of morbidity and mortality in hospitalized patients with various life threatening complications. Hence, this study was aimed to determine the incidence, risk factors of CAUTI in a tertiary care hospital so as to find out better preventive measures to reduce the prevalence of CAUTI and their complications so as to reduce the hospital stay and mortality. Materials and methods: Present study included 200 adult patients who received indwelling urethral foley’s catheter and urinary drainage system in various wards in Government General Hospital, Nizamabad from Jan 2015 - May 2016. Patients were diagnosed to have CAUTI according to CDC guidelines to study its incidence and associated risk factors which were analyzed using multi variate analysis. Results: Overall incidence of CAUTI was 59%. The incidence of CAUTI was maximum (70.58%) in the age group of 51-70 years. The incidence of CAUTI was more (69.44%) in females and was directly proportional to the duration of catheterization. The high incidence in the present study reflects the practice of frequent disconnections of urinary closed systems. Multi-variate analysis shows age, duration of catheterization, catheter- tubing disconnections, absence of antibiotic use and renal Md. Yousuf Khan, C. Venkateshwarlu, G. Sreenivas, P. Rahul. Study of incidence and risk factors of urinary tract infection in catheterized patients admitted at tertiary care hospital, Nizamabad, Telangana State, India. IAIM, 2016; 3(8): 83-92. Page 84 insufficiencies as important risk factors for CAUTI. 88.66% of CAUTIs were asymptomatic among 75 clinically evaluable CAUTIs. Conclusion: CAUTI is an important preventable hospital acquired infection seen in all age groups however incidence increases with age, common in both sexes, incidence can be reduced by minimizing the catheter procedures, taking the maximum aseptic precautions, reducing the duration of catheterization and avoiding frequent disconnections, this becomes more significant in patients with underlying renal disease , prophylactic antibiotics prevent CAUTI. As most of the CAUTI are asymptomatic, all catheterized patients should be screened for CAUTI and be treated depending upon antibiotic sensitivity of uropathogens.
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Morquio syndrome an autosomal recessive mucopolysaccharoidosis (MPSs) including Type IVA, a deficiency of N-acetylgalctosamine-6- sulfatase and Type IVB a deficiency of β-galactosidase. Plain films of the entire spine, pelvis, chest, knees, hip, and knees demonstrated the characteristic skeletal changes of this disease. The main abnormalities were platyspondyly, genu valgum deformity. Radiographs are crucial to provide substantial information about evolution of the skeletal and joints changes, and the rehabilitation strategies to be followed. From detailed history, physical examination, investigations, and treatment, different clinical, radiographic and biochemical studies it is clear that Morquio’s disease is an inherited error of MPS metabolism characterized by deficiency of galactose 6-sulfate sulfatase activity.
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germination of S. emarginatus in vitro cotyledon explants in BAP/Kn/TDZ (1.0-3.0 mg/L) supplemented MS medium and (2) in plant treatment with BAP/Kn/TDZ (3.0 mg/ L) in combination of 1AA (0.5 mg/L) of the cotyledon explants of plants and maintained under sterile conditions. While the former method resulted in as many as (7.5±8.6 shoot buds) from the cotyledonary explants within four weeks, the latter yielded on average approximately 8 shoot buds from each treated node in eight weeks. The cytokinin treatment in plant consisted of placing sterile filter paper moistened with sterile distilled water over the node and adding different concentrations of 6- benzylaminopurine. The best results for shoot bud regeneration were obtained with cotyledons, when cultured in the presence of (0.5 mg/L) IAA in combination with (3.0 mg/L). The shoots elongated and rooted directly in vermiculite after a pulse treatment with IBA (2.5 mg/L) for 15 min. Fungus growth, a serious problem in S. emarginatus tissue culture, was controlled using a fungicide, Bavistin, along with elimination of organic nutrients from the growth medium.
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A field experiment was conducted in a farmer’s field in the Red and Laterite zone of West Bengal to evaluate the effect of integrated use of FYM and concentrated organic manures and chemical fertiliser on dynamics of potassium in soil in relation to growth and yield of component crops viz., Potato, Sesame and Rice. Three levels of chemical fertilisers viz., (i) 75% of the RDF, (ii) 100% of the RDF, and (iii) 150% of the RDF and three levels of organic manures (i) Control- applying no 0rganic manure; (ii) FYM at 20 ton/ha, and (iii) a consortium of concentrated organic manure were applied in potato after which sesame and rice were grown with the residual nutrients. Under all the three crops, application of higher doses of chemical fertilizer resulted in greater decrease in soil pH and increase in soil EC, soil OC, exchangeable, water soluble and non-exchangeable K contents of the soil. Among the two organic manures applied, the values of these parameters of the soil under all the three component crops were the highest under application of FYM. The highest pooled mean value of soil pH and lowest EC, OC, exchangeable, water soluble and non-exchangeable K contents of the soil, irrespective of the component crop in the cropping sequence, was observed under RDF75 without any organic manure and the highest under RDF150 with application of FYM. Pearson correlation co-efficient among different soil and plant parameters suggested strong relationship among themselves and K content of rice shoots, and straw of the component crops. Under limited availability of FYM, commercially available sea weed extract based concentrated organic manures could be handy and effective.
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Biochemical constituents of body of the freshwater fish Mystus cavasius were greatly influenced by the breeding activity. Protein was estimated from testes, liver and muscle at different breeding phases. There was an increase in protein levels of testes during maturation of testes was observed and it was related to simultaneous decrease in the liver and muscle. While in immature and preparatory stage, it was found to be the storage phase of protein in muscle and liver. Depletion of protein in muscle and liver and is transferred to testes during maturation has been found to be significant.