Subject(s)
Humans , Anticonvulsants , Epilepsy , Valproic Acid/pharmacology , Anticonvulsants , Benzodiazepines , Carbamazepine , Phenytoin/pharmacology , Phenobarbital , Primidone , VigabatrinABSTRACT
We report a 66 years old male, with an ophtalmologic history of long sightedness, admitted to the hospital due to paroxysmal atrial fibrillation crises in the context of a coronary heart disease. He was treated with iv amiodarone, receiving a total dose of 6 g in 72 hours. After the third day of treatment, the patient noticed a correction of his long sightedness and 24 h later, he complained of blurred vision and orbital frontal headache. Visual field examination revealed a concentric retraction of visual field and a centrocecal scotoma in both eyes. Amiodarone was withdrawn and dexametasone treatment was begun. Three days after amiodarone discontinuation, sight improved and visual field returned to normal. Although retrobulbar neuritis has been associated to various drugs, amiodarone has not been considered as a possible agent
Subject(s)
Humans , Male , Aged , Amiodarone/adverse effects , Optic Neuritis/chemically induced , Pacemaker, Artificial , Dexamethasone/therapeutic use , Hyperopia/complications , Atrial Fibrillation/surgery , Atrial Fibrillation/etiology , Atrial Fibrillation/drug therapy , Optic Neuritis/drug therapyABSTRACT
Se presentan los resultados de la revisión realizada de veinte casos de síndrome de Guillain-Barre estudiados y tratados en el servicio de Neurología del Hospital Carlos Van Buren en el período comprendido entre diciembre de 1983 y agosto 1988. Especial énfasis se realiza en el análisis de las formas clínicas de presentación, el compromiso diferencial de pares craneales, los hallazgos del líquido céfalo raquídeo y su perfil temporal evolutivo conjuntamente con la información proporcionada por los estudios electrofisiológicos. Las sugerencias del análisis epidemiológico son discutidas