Effect of Seed Extract of Amomum Cardamomum on Renal Function in Alloxan Induced Diabetic Rats.

The present work was undertaken to investigation, the effect of ethanolic seed extract of Amomum cardamomum on blood urea nitrogen, creatinine, and uric acid in alloxan induced diabetic rats. Ethanolic seed extract of Amomum cardamomum was administered orally (50 mg/kg body weight) for 7,15,30,45 and 60 days. Treatment with Amomum cardamomum resulted in significant reduction of serum urea (p<0.001), creatinine (p<0.001) and uric acid (p<0.001); while increment in serum total protein (p<0.001) and comparable with that of alloxan induced diabetic rats and control groups. The results clearly show, the decreased urea, creatinine, uric acid and improvement in serum protein activity with the treatments have been attributed to improve renal function.

Nanomedicine : Future Prospective in Disease Diagnosis and Preventions.

Medical practice is about to enter a new era focused on the nanoscale and the practice of ‘‘nanomedicine.’’ Nanomedicine may be defined as the monitoring, repair, construction, and control of human biological systems at the molecular level, using engineered nanodevices and nanostructures. Nanomedicine is, in a broad sense, the application of nanoscale technologies to the practice of medicine, namely, for diagnosis, prevention, and treatment of disease and to gain an increased understanding of complex underlying disease mechanisms The potential medical applications are predominantly in detection, diagnostics (disease diagnosis and imaging), monitoring, and therapeutics. The availability of more durable and better prosthetics and new drug-delivery systems are of great scientific interest and give hope for cancer treatment and minimum invasive treatments for heart disease, diabetes and other diseases. Many novel nanoparticles and nanodevices are expected to be used, with an enormous positive impact on human health. Nanotechnology provides the field of medicine with promising hopes for assistancassistance in diagnostic and treatment technologies as well as improving quality of life. Humans have the potential to live healthier lives in the near future due to the innovations of nanotechnology. Some of these innovations include: Disease diagnosis, Prevention and treatment of disease , Better drug delivery system with minimal side effects , Tissue Reconstruction. The vision is to improve health by enhancing the efficacy and safety of nanosystems and nanodevices. Products based on nanotechnology in medicine and medical technology are reaching the market, with an anticipated enormous positive impact on human health, in the coming years. Ethical and moral concerns also need to be addressed in parallel with the new developments. Today, nanotechnology and nanoscience approaches to particle design and formulation are beginning to expand the market for many drugs and are forming the basis for a highly profitable niche within the industry, but some predicted benefits are hyped.