A Study Of Clinical Profile Of Swine Flu Patients In The Outbreak Of 2015 In Tertiary Care Centre At Jabalpur

AIM:To study the clinical profile of H1N1 positive patients admitted in Swine flu ward in NSCB Medical College, Jabalpur in outbreak of 2015. MATERIALS & METHODS: All H1N1 positive patients admitted in NSCB MCH, Jabalpur were analysed retrospectively with respect to morbidity and mortality and possible clinical conclusions were derived. RESULTS: Of 64 H1N1 positive patients, 23 died. Cough, fever & dyspnoea were main symptoms in all patients including those under mortality group. Those with a duration of stay in hospital >10 days had least mortality. Highest mortality seen in patients with duration of stay between 1-10 days. 40 (62.5%) of 64 patients had some co-existing illness of which Anemia & DM were most common. 16 (69.5%) out of 23 patients who died had some co-existing illness of which DM was associated with 9 patients, Anaemia with 8 & Hypertension with 7 patients. 25 (39%) of 64 patients developed some complications of which ARDS & encephalopathy had higher mortality as compared to Renal failure & MODS. Of 23 patients who died, 18 (78%) developed some complication. CONCLUSION: Knowing the potential of Influenza virus for genetic mutations, it is difficult to find a stereotype pattern of illness as also documented by studies done in past. Good clinical skills always carry high value in suspecting & defining H1N1 infection & its complications. Co-existing illness must be taken special care of during an outbreak of Swine flu. Community education, timely immunization of those at high risk & early referral can save many lives

Bilateral Symmetrical Basal Ganglia Calcification with Atypical Presentation: A Case Series.

Physiological intracranial calcification is asymptomatic and is detected incidentally by neuroimaging. Pathological basal ganglia calcification (BGC) is caused by various causes such as metabolic disorders, infectious and genetic diseases, and others. The most common causes of pathological BGC are hypoparathyroidism and pseudohypoparathyroidism. We present three cases of bilaterally symmetrical BGC associated with hypoparathyroidism. All of them presented with seizures as the only presentation without any signs of hypocalcemia and without extrapyramidal features. One should not rule out hypoparathyroidism in the absence of other signs of hypocalcemia and extrapyramidal features. Biochemical analysis pertaining to hypoparathyroidism must be done. Timely treated patients can have a good prognosis.