ABSTRACT
Background and aim: Biochemical parameters in Covid 19 have not been studied extensively. The main aim of this study was to establish a correlation between various biochemical markers with their role in the prognosis of Covid infected patients along with their diagnostic importance in severity and early detection of severity to overcome the mortality in intuitional patients. Material and methods: This study was conducted at Pt.J.N.M. Medical College, Raipur and associated B.R.A.M. Hospital, Raipur a dedicated Covid hospital during the current epidemic. The samples available were divided into two groups namely mild and severe according to their hospital admission and duration. Results: In our study it was found that Interleukin-6 and Ferritin was significantly (p<0.05) raised in sever Covid patients when compared with mild and moderately affected patients. The other biochemical parameters were also influenced by Covid-19 as Covid affects various systems in human body. Conclusion: By this study we want to establish the role of various markers for early detection of and prevention of severity in known cases of Covid-19. The investigation of effective laboratory biomarkers as a role in classifying the patients based on their risk is important for prognosis and treatment of disease.
ABSTRACT
Objective: To compare the Children’s Color Trail Test scores in children with and withoutAttention Deficit Hyperactivity Disorder to assess its diagnostic performance in assessingattention-deficit. Methods: 50 children with Attention Deficit Hyperactivity Disorder(diagnosed as per Diagnostic and Statistical Manual, 5th edition) and 50 age- and sex-matched children underwent Test 1 and Test 2 of the Children’s Color Trail Test. A ReceiverOperating Characteristics curve was constructed for the diagnostic accuracy of Children’sColor Trail Test in Attention Deficit Hyperactivity Disorder. Results: The Receiver OperatingCharacteristics curve showed a score ≤32 for Children’s Color Trail Test 1 [AUC: 0.8 (0.71 to0.87); P<0.001] and score ≤40 for Children’s Color Trail Test 2 [AUC: 0.85 (0.77 to 0.92);P<0.001] as the best cut-off for diagnosing Attention Deficit Hyperactivity Disorder.Conclusion: Children’s Color Trail Test is a promising tool for diagnosing attention deficit,and could be used in settings where parent or teacher reports are not available
ABSTRACT
Background: MTP Act no 34 of 1971 has been defined as Legal termination of pregnancy before the age of viability of fetus that is 20 weeks of gestation. There is a need to find a medical agent which can help in the process of abortion by speeding it up, with minimal side effects. The objective of this study was to compare the efficacy of I.M carboprost and intravaginal Misoprostol and to evaluate the safety profile of I.M carboprost and Intravaginal Misoprostol. To compare the cervical dilatation caused by I.M carboprost and intravaginal Misoprostol and to compare the blood loss and adverse effects of I.M carboprost and Intravaginal Misoprostol.Methods: Prospective randomized experimental study including pregnant women up to 12 weeks of gestation opting for M.T.P. Study conducted on 200 patients selected from patients admitted in MGM Medical College and M.Y. Hospital, Indore and Kalyanmal Hospital, Indore during the period July 2014 to March 2015. They were randomly divided into 2 groups. Group A who received intramuscular injection of 250 mcg of caboprost or Group B,which received 400 mcg of vaginal Misoprostol 4 hours prior to suction evacuation.Results: Intravaginal misoprostol achieves better cervical dilatation compared I.M carboprost which is statistically significant. Misoprostol is associated with higher blood loss as compared to I.M carboprost which is associated with nausea/vomiting & more likelihood of loose stools and abdominal cramps which is proved statistically.Conclusions: Intravaginal misoprostol is associated with higher blood loss as compared to I.M carboprost which is significant but intravaginal misoprostol achieves more cervical dilatation and causes less adverse events than I.M carboprost which is statistically more significant and therefore intravaginal misoprostol is the drug of choice for cervical priming prior to surgical abortion in terms of both efficacy and safety.