ABSTRACT
Objectives: red cell distribution width [RDW] and neutrophil-to-lymphocyte ratio [NLR] are the two markers used to determine risk of mortality and adverse cardiovascular outcomes in patients with acute myocardial infarction. The relationship between RDW, NLR, and left ventricular [LV] systolic functions has not been reported. In this report, we aimed to investigate the relationship between RDW, NLR, and LV systolic function in anterior ST-segment elevation myocardial infarction [STEMI] patients who underwent primary percutaneous coronary intervention [PCI]
Methods: RDW and NLR were measured on admission in 106 STEMI patients treated with primary PCI. Patients were divided into two groups according to left ventricular ejection fraction [LVEF], as Group I [systolic dysfunction, LVEF <50%] and Group II [preserved global left ventricle systolic function, LVEF P50%]. The first group included 47 patients and the second group included 59 patients
Results: mean RDW and NLR were significantly higher in Group I compared to Group II [13.7 +/- 0.9% vs. 13.4 +/- 0.7%, p = 0.03 and 5.86 [range, 0.66-40.50] vs. 2.75 [range, 0.51-39.39], p = 0.013, respectively]
Conclusion: increased RDW and NLR on admission, in anterior STEMI patients treated with primary PCI are associated with LV systolic dysfunction