ABSTRACT
O angiohistiocitoma com células multinucleadas é dermatose vascular benigna, caracterizada pela presença de múltiplas pápulas eritêmato-violáceas, agrupadas, acometendo preferencialmente alguma extremidade. Sua histologia evidencia hiperplasia vascular com proliferação de células do tecido conjuntivo, associada à presença de células gigantes multinucleadas. Acomete principalmente mulheres após a quarta década de vida. Relata-se o primeiro caso dessa entidade na América Latina e discute-se os principais aspectos clínicos, histopatológicos e imuno-histoquimicos
Subject(s)
Humans , Female , Adult , Giant Cells/ultrastructure , Perna , Skin Diseases, Vascular , Vascular Neoplasms , Dendritic Cells/ultrastructure , Diagnosis, Differential , Immunohistochemistry , Sarcoma, Kaposi/diagnosis , Skin Diseases/diagnosis , Vascular Neoplasms/diagnosis , Vascular Neoplasms/etiology , Vascular Neoplasms/pathologyABSTRACT
One hundred and twenty-six patients with LE were studied. They were distributed as follows: 84 with DLE, 13 with SALE and 29 with SLE. Biopsies from the skin lesions were performed and submitted to DIF. Positive results were equal to 69,61.5 and 72.4 percent of the DLE,SALE and SLE cases, respectively. These data are in accordance with the literature. IgM was the most frequently found immunoglobulin, followed by the association IgM+C3.