ABSTRACT
Diseases prevention and health promotion have been standing out in moderm dentistry. Biofilm control still is a major challenge to clinicians, independently of treatment that will be done. Success during and after treatment is related to professional care and to patient cooperation. Mechanic methods to maintenance of oral hygiene cannot be substituted, but , sometimes, it is difficult or even impossible to control biofilm suitably. At these cases, appropriated use of chemistry agents should be a good alternative as co adjuvant in different treatments. Chlorhexidine is the product that has been showing best clinics results at biofilm control when compared to others topical antimicrobial agents. Chlorhexidine has different applicability since it can be used as a surface and root canal disinfectant and effective antimicrobial at biofilm control, gingivitis and periodontal disease prevention and treatment, control of S. mutans colonization, caries prevention and prevention of possible systemic infection for bacteria that could occur after simple proceedings like suture removal. Chlorhexidine gluconate should be used for prevention or therapeutics at different presentations like solution, varnish, sub-gengival solution, intra oral gadgets, and others. Protocol of concentration and period of application vary according the use and it must be proposed according to individual needs of each patient