ABSTRACT
Background: The incidence/prevalence of tuberculosis [TB] is reported to be high in the Sahariya tribe of North Central India. The outbreaks of different drug-resistant isolates of Mycobacterium tuberculosis emphasized the need for continuous monitoring of resistance to anti-tuberculosis drugs. This study aimed to assess the profile of multidrug resistant TB among the Sahariya tribe and their non-tribal neighbors for first line drugs through field-based investigations.
Methodology: A total of 274 sputum positive pulmonary TB individuals were enrolled and studied for their drug susceptibility profile by the proportion method. Results: A total of 21 cases from Sahariya and 6 from non-tribes were identified with MDR-TB. Thus Sahariya tribe showed a 1.95-fold increased risk of developing drug resistance than non-tribes. Significant differences were observed for developing drug sensitivity between Sahariya males and females when analyzed for resistance developed to any drug and overall drug resistance vs. sensitive isolates, respectively
A 4.46-fold risk was found for MDR-TB among the smokers of Sahariya tribe, whereas, the non-tribes did not show any significant association
Conclusion: The drug susceptibility profile developed in the present study indicates that drug-resistant tuberculosis is emerging as a serious public health concern in Sahariya tribe. Urgent and effective control measures and better management policies are needed for the prevention of MDR-TB in the tribe
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Tuberculosis , Prevalence , Mycobacterium tuberculosisABSTRACT
The laser is once again poised to revolutionize ophthalmology, this time in the field of lacrimal surgery. At many centers, transnasal laser-assisted dacryocystorhinostomy is currently being performed and evaluated as a less invasive method for lacrimal bypass surgery than the traditional method. We have performed this new operation on ten patients. Advantages include avoidance of a cutaneous scar, reduction of surgical trauma and bleeding, minimal postoperative pain, and a shortened period of recovery. The surgical success rate of 90% is comparable to that of conventional dacryocystorhinostomy
Subject(s)
Humans , Lasers/methods , Nasolacrimal Duct/surgery , General Surgery/methods , Silicon/statistics & numerical dataABSTRACT
Weill-Marchesani syndrome is a rare systemic connective tissue disorder, manifested by short stature. brachydactyly, and microspherophakia. Although the syndrome is known to occur with relative frequency in the Middle East, no cases from Saudi Arabia have been published up to date. We present a case with the typical manifestations of this syndrome, showing in addition brachycephaly, depression of the nasal bridge, and bilateral "paving stone" retinal degenerations. Bilateral intracapsular lens extractions were performed without any complications