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Abstract@#The integration of health education into physical education in colleges is an important carrier to achieve the goal of school health education, and an inevitable requirement for improving health literacy of college students. Exploration and construction of one curriculum content system integrating health knowledge and sports skills, mental health and sports spirit, basic theory of physiology, sports injury and disease prevention. The integration of health education into physical education includes curriculum and material design, classroom based teaching process, as well as teaching assessment inside and outside the classroom, developing a multi faceted, multi level and multi angle optimized implementation approach, aiming to explore the joint connection of health education and physical education, the implementation of Lide Shuren can better achieve the cultivation of students health awareness and healthy lifestyle, and lay a solid foundation for lifelong health.
ABSTRACT
Objective@#To understand physical exercises and associated factors among college students COVID-19 pandemic, and to provide a reference for promoting physical exercise of college students at home.@*Methods@#A convenient questionnaire survey was used to investigate the physical exercise and associated factors of 1 132 college students in 6 colleges in Beijing.@*Results@#A total of 1 033(91.25%) college students participated in physical exercise; with an average of(3.33±1.99)times per week, the length of each exercise was (39.24±13.23)min, and the subjective sense of exercise intensity was(2.61±0.99). Differences in exercise frequency, duration and intensity differed significantly by gender(P<0.05). Differences in exercise frequency were significantly by grades and places of residence(P<0.05). The exercise items of college students differed by genders and places of residence were statistically significant(P<0.05). Students with different exercise motivations showed significant differences in exercise behaviors(P<0.05). Multivariate Logistic regression analysis showed that grade, lack of interest in exercise, limited venues, incomplete equipment, family sports atmosphere, and school requirements were associated with participation in physical exercise behavior at home(P<0.05).@*Conclusion@#The status of home physical exercise for college students needs to be improved. It is necessary to combine college students exercise motivation and characteristics of exercise items based on school physical education,and to establish a family-school-society network interactive platform to form an effective linkage mechanism to promote college students active participation in physical exercise at home.
ABSTRACT
The clinical significance of a myetoperoxidase (MPO) gene polymorphism and inducible nitric oxide synthase (iNOS) expression in cirrhotic patients with hepatopulmonary syndrome (HPS) was explored. Enrolled subjects were divided into three groups according to their disease/health conditions: the HPS group (cirrhotic patients with HPS;n=63), the non-HPS group (cirrhotic patients without HPS;n=182), and the control group (healthy subjects without liver disease;n=35). The distribution of the MPO -463 G/A genotype and its relationship with iNOS expression in a typical cell block from as-citic fluid were detected by immunohistochemistry and polymerase chain reaction-restricted fragment length polymorphism analysis (PCR-RFLP). In the HPS group, the partial pressure of oxygen in blood and ascitic fluid was significantly decreased (8.95±1.58 kPa and 6.81±0.95 kPa, respectively;both P<0.01), while the partial pressure of carbon dioxide significantly increased (4.62±0.20 kPa and 5.92±0.45 kPa, respectively;P<0.01). MPO and iNOS levels were significantly increased in the HPS group as compared with the non-HPS group. These increases were even more remarkable in ascitic fluid (41.36±11.62 and 13.23±4.81 μg/L;10.27± 3.2 0 and 4.95±1.12 μg/L) than in blood (16.66±5.24 and 4.87±1.73 μg/L;5.79±2.31 and 2.35±0.84 μg/L). The distribution of the MPO genotypes GG, GA, and AA were 76.2%, 22.2% and 1.6% in the HPS group, and 57.7%, 37.9% and 4.4% in the non-HPS group (P<0.05). The expression of iNOS was significantly higher in patients with the G alleles (G/G and G/A) (61.54%, 48/78) than in patients with A alleles (G/A and A/A) (38.46%, 30/78) (P<0.01). It was suggested that the expression levels of iNOS and MPO were correlated with HPS-induced hypoxemia. The MPO-463 G/A mutation might be a protective factor that prevents the development of HPS. The MPO might be involved in the regulation of iNOS expression. In humans, MPO pathways, the iNOS/NO system, and their interaction might have an impact on the occurrence and development of HPS.