Peroxidative damage and cancer colon risk in animals fed repeatedly heated cotton seed oil

The present study was conducted experimentally to assess the potential health hazards of ingesting repeatedly heated frying oil. Ten male albino rats were fed rodent chow containing 20% [w/w] of either fresh or repeatedly heated oil for three months. Thiobarbituric acid reactive substance concentrations [TBARS] were significantly higher in repeatedly heated oil samples compared to fresh oil samples. Feeding rats with repeatedly heated oil resulted in significant increase in heptosomatic and nephrosomatic indices with significantly higher serum levels of alkaline phosphates activity and urea creatinine as compared to those fed with fresh oil indicating to nutritional hepatic and renal cellular impairment