ABSTRACT
Objectives: To determine correlation between blood levels of high sensitivity c-reactive protein [Hs CRP] and severity of coronary artery disease [CAD] on coronary angiography measured through Gensini scoring system
Study type, settings and duration: The descriptive case study was conducted at Rawalpindi institute of cardiology. The duration of study was six month
Patients and Methods: Adult patients of both genders between age 25 to 60 years visiting to outpatient department of the institute and registered for coronary angiogram were included. From each of the enrolled patient about 5cc venos blood sample was collected and Hs-CRP was performed. Severity was measured through Gensini score after coronary angiography. Angiographic Gensini scores were correlated with Hs-CRP using Pearson's correlation [2-tailed]. Value of < 0.05 was considered statistically significant
Results: Total 87 patients fulfilling the inclusion criteria were enrolled among them 81.6% [n=71] were males and 18.4% [n=16] were females. The correlation coefficient was found to be 0.043, implying that there is negligible relationship between Hs-CRP and Gensini scores at p= 0.696
Conclusion: There is no significant correlation between Hs-CRP and severity of CAD measured through Gensini scores on coronary angiography