Role of pet/ct in assessment of colorectal carcinoma

Background: colorectal cancer is the second most common cause of cancer in women [9.2% of diagnoses] and the third most common in men [10.0%], it is the fourth most common cause of cancer death after lung, stomach, and liver cancer

Aim of the Work: the goal of this study was to elucidate the role of 18F-FDG PETCT in evaluation of colorectal cancer

Patients and Methods: twenty five patients with histopathologically proven colorectal primary malignancy were evaluated for suspected local recurrence and metastasis. No age predilection and both sexes were included, clinical history, image follow-up, tumor markers, and pathological reports were reviewed for gold standard

Results: the final diagnosis of distant metastasis and/or local recurrence in post-therapeutic cancer colon was evident in 70% of our patient population with PET/CT sensitivity of 95.6%, specificity of 91.4%, [NPV] of 88.9%, [PPV] of 96.7%, and diagnostic efficacy of 94.4% and CT sensitivity of 62.6%, specificity of 48.6, [NPV] of 33.3% [PPV] of 76.0%, and diagnostic efficacy of 58%

Conclusion: PET/CT is a better method to evaluate post-therapeutic colorectal cancer patients

Role of magnetic resonance imaging and ultrasonography in diagnosis and follow up rheumatoid arthritis in hand and wrist joints

Aim of the work: to compare the role of ultrasonography and magnetic resonance imaging in the diagnosis of wrist joint affection in patients with rheumatoid arthritis

Patients and methods: this study included 50 patients diagnosed as rheumatoid arthritis [41 females and 9 males] with mean age 43 years; they were subjected to high resolution ultrasound and MRI of the wrist joint for the dominant affected wrist clinically. Comparison and correlation between both modalities was done

Results: our results showed agreement between ultrasound and MRI in the assessment of synovial inflammation, activity and bone erosions in wrist joint in rheumatoid arthrtis patients

Conclusion: we concluded that both modalities were comparable and close to each others as regards the bony erosions and synovial hypertrophy and inflammation in the wrist joints in patient with rheumatoid arthritis and the ultrasound was useful tools in detection of erosions and synovial inflammation so can be used in patients without erosions on conventional x ray and also can be used in follow up and monitoring the patients with established diagnosis of rheumatoid