ABSTRACT
We report the clinicopathological features and outcome of four cases of carcinoma of the male breast diagnosed at the University Hospital of the West Indies between 1988 and 1998. Male breast cancer is most commonly seen in men over age sixty years, and it exhibits the same prognosis, stage for stage, as the disease in females. However, some researchers report overall poorer survival in men, and explain this on the basis of advanced disease at presentation. Other researchers maintain that the majority of breast cancers in males present at early stages, and exhibit survival similar to that in females. The published literature concerning this uncommon malignancy is reviewed, and the data are compared with the features of our cases.
Subject(s)
Aged , Humans , Male , Middle Aged , Carcinoma, Ductal, Breast , Breast Neoplasms, Male , Incidence , Risk Factors , Carcinoma, Ductal, Breast , Breast Neoplasms, MaleABSTRACT
The POEMS syndrome is an unusual disorder manifesting primary as peripheral sensorimotor neuropathy in association with a monoclonal gammopathy. The importance of its recognition is that significant clinical improvement may result from localization and treatment of the underlying plasma cell tumour.
Subject(s)
Humans , Middle Aged , Male , Pigmentation Disorders/diagnosis , Plasmacytoma/complications , Endocrine System Diseases/diagnosis , Neuritis , Plasmacytoma/therapy , Edema/etiology , Erectile Dysfunction/etiology , SyndromeABSTRACT
Glanzmann's thrombasthenia is a rare congenital disorder of platelet function manifesting as defective primary haemostasis. Bleeding episodes often require platelet transfusions, and allo-immunization to donor platelets may occur. The problems of ensuring adequate haemostatic potential for delivery of an allo-immunized pregnant female with Glanzmann's thrombasthenia are presented