ABSTRACT
Objective To patients with neonatal dacryocystitis underwent left Ofloxacin Gel, Tobramycin and Dexamethasone Ophthalmic Ointment and lacrimal surgery combined with treatment effects were observed.MethodsIn Ningxia Hui Autonomous Region Qingtongxia City People's Hospital during December 2015 to December 2016 for dacryocystitis in 130 cases according to the data analysis, using different treatment schemes were divided into two groups, 65 cases underwent lacrimal surgery as control group, 65 cases and left Ofloxacin Gel, Tobramycin and Dexamethasone Ophthalmic Ointment combined treatment as the observation group, blocking characters and comparison of complications two groups of clinical curative effect, lacrimal duct.ResultsIn the observation group, the total effective probability of 96.92% higher than the control group of 80.00%(P<0.05), and the nasal deformity, nasolacrimal duct, lacrimal bone deformity multiple adhesions or obstruction and lower incidence of membranous obstruction of lacrimal duct is lower than that of control group (P<0.05);the total complication rate in the observation group(3.08%) than the control group(21.54%)low (P<0.05).ConclusionNeonatal dacryocystitis underwent left Ofloxacin Gel, Tobramycin and Dexamethasone Ophthalmic Ointment and lacrimal surgery combined therapy can improve the clinical symptoms and characteristics of lacrimal duct obstruction, and reduce postoperative complications, which may be of clinical promotion and application.
ABSTRACT
Objective To evaluate the clinical efficacy of combined pilocarpine eye drops in the treatment of traumatic angle recession glaucoma.MethodsThe clinical data of the patients were collected and analyzed retrospectively.The data collection time was December 2015 to December 2016.Were randomly divided into two groups according to the time of admission, the control group (38 cases) received routine treatment, the observation group (40 cases) treated with conventional therapy combined with pilocarpine eye drops.The IOP and pupil diameter of two groups were observed and compared.ResultsAfter treatment, two groups of patients with intraocular pressure were significantly decreased, compared with the group before treatment, there were statistically significant differences, and different time after the treatment were compared between the observation group were significantly lower than the control group, the difference was significant (P<0.05);after two 7d of treatment group were significantly reduced compared to the diameter of the pupil.Compared with the group before treatment, there were statistically significant differences, and different time after the treatment were compared between the observation group were significantly less than the control group, the difference was significant (P<0.05);efficiency evaluation results of two groups under different treatment, the observation group treated a total of 21 cases invalid, only 2 cases, the total effective rate was 95.00%, and there was no statistic difference between control group (P<0.05).ConclusionThe conventional therapy combined with pilocarpine eye drops on injury caused by angle recession glaucoma patients for treatment can significantly reduce intraocular pressure, miosis, improve efficiency.
ABSTRACT
Objective To observe and compare the effect of lyceum barbarum combined with corticosteroids and corticosteroids alone on the treatment of acute anterior uveitis(AAU), to explore the mechanism of lyceum barbarum could auxiliary treat AAU.Methods 60 cases with AAU were randomly divided into lyceum barbarum combined with corticosteroids treatment group(combination therapy group), simple corticosteroids treatment group(cortisol treatment group) and health control group.Health control group consists of healthy volunteers.Results The efficient rate of the combination therapy group in the early treatment stage(1 week) was 86%, the cortisol treatment group was 62%.In the late stage treatment(2 weeks) the efficient rate was 98% and 80% in the cortisol treatment group.The total efficiency rate in the two groups was significant difference(P<0.05).The level of IL-10、TNF-α、 IFN-γ and IL-23 in the combination therapy group and cortisol treatment group were significantly higher than those in healthy control group in AAU attack period(P<0.01), the levels of these cytokines were significantly decreased after treatment(P<0.01).IL-10 was significantly higher in patients before treatment than that in healthy control group(P<0.01), IL-10 in cortisol treatment group was increased than that before treatment, IL-10 in combination therapy group was decreased after treatment than that before treatment(P<0.05).The level of IFN-γ in the combination therapy group and cortisol treatment group were higher than that in healthy control group after treatment(P<0.05).Conclusion The levels of IFN-γ, IL-10, TNF-α, IL-23 in acute attack stage in AAU patients were significantly higher than those after treatment and other people with physical examination, while the treatment of lyceum barbarum combined with hormone, IFN-γ and IL-23 levels decreased significantly, the effect was obvious, which is worthy of promotion.