Research progress of oxidative stress and acute pancreatitis / 国际外科学杂志

Acute pancreatitis (AP) is a common clinical acute abdominal disease, usually with local complications such as pancreatic necrosis, pseudocysts, and abdominal abscesses, as well as systemic inflammatory response syndrome and multiple organ dysfunction syndrome. It is dangerous, difficult to treat, and the prognosis is poor. Although significant progress has been made on the pathogenesis of AP, its specific mechanism is still unclear. In the past few decades, many studies have emphasized the role of oxidative stress in acute inflammatory response. This article clarified the role of oxidative stress in the occurrence and development of AP by introducing oxidative stress to break the cellular Ca 2+ balance, participate in the stimulation of transcription factor activation and excessive release of inflammatory mediators and introduces the application of antioxidant adjuvant therapy in the treatment of AP.

Research status of acinar cell cystadenoma of the pancreas / 中华消化外科杂志

Acinar cell cystadenoma (ACA),also referred to as acinar cystic transformation,is a rare and newly recognized cystic lesion of the pancreas.This cystic lesion displaying apparent acinar cell differentiation and lacking of distinct cellular atypia was accepted as the benign counterpart of acinar cystadenocarcinoma.However,the exact etiopathogenesis of ACA is still not clear.