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1.
West China Journal of Stomatology ; (6): 596-600, 2014.
Article in Chinese | WPRIM | ID: wpr-231796

ABSTRACT

<p><b>OBJECTIVE</b>This preliminary study aims to investigate the effects of titanium and titanium alloy micro-nano-dimensional topography on the biological behavior of osteoblasts in vitro.</p><p><b>METHODS</b>Electrolytic etching (EE) method was used to produce micro-nano dimensional titanium surfaces. The surfaces were observed to determine their effects on the adhesion, proliferation, cell morphology, and alkaline phosphatase (ALP) activity of osteoblasts.</p><p><b>RESULTS</b>The surfaces of the titanium and titanium alloy groups exhibited higher adhesion and proliferation of osteoblasts than those of the mechanical group. The titanium surface was covered with a group of cells, a large number of filopodia, and functional particles. The ALP activity of the titanium group was significantly higher than that of the titanium alloy and mechanical groups.</p><p><b>CONCLUSION</b>EE method in pure titanium and titanium alloy surfaces result in bowl-like nests and nanostructures of different diameters and depths. The diameters of the pure titanium and titanium alloy surfaces range from 30 to 50 μm and 5 to 8 μm, respectively. The former is more conducive to promote the proliferation and differentiation of cells.</p>


Subject(s)
Humans , Alloys , Cell Differentiation , Cell Proliferation , Dental Etching , Nanostructures , Osteoblasts , Prostheses and Implants , Surface Properties , Titanium
2.
Chinese Journal of Stomatology ; (12): 722-725, 2010.
Article in Chinese | WPRIM | ID: wpr-243105

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the treatment and prevention of infection after alveolar crest onlay bone graft.</p><p><b>METHODS</b>From January 2006 to May 2010, 11 infection cases after onlay graft on alveolar crest were reviewed to evaluate the infection time, clinical situation, treatment measure, and therapeutic effect.</p><p><b>RESULTS</b>The infection of all 11 cases occurred about 15 days after bone graft, which showed either soft tissue fistulae or bone graft exposure in the oral cavity. Three cases failed because of persistent infection. The infection of the other 8 cases was controlled after a series of comprehensive therapy, and most of the bone graft was reserved and implant restoration finally completed.</p><p><b>CONCLUSIONS</b>After the effective and comprehensive therapy, infected bone graft can be reserved. But to ensure the survival rate of bone graft, the most important thing is to prevent infection in perioperative period.</p>


Subject(s)
Humans , Alveolar Ridge Augmentation , Bone Transplantation , Dental Implants , Follow-Up Studies , Infections , Inlays , Retrospective Studies
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