ABSTRACT
OBJECTIVE@#To design and construct a graphene oxide (GO)/silver nitrate (Ag3PO4)/chitosan (CS) composite coating for rapidly killing bacteria and preventing postoperative infection in implant surgery.@*METHODS@#GO/Ag3PO4 composites were prepared by ion exchange method, and CS and GO/Ag3PO4 composites were deposited on medical titanium (Ti) sheets successively. The morphology, physical image, photothermal and photocatalytic ability, antibacterial ability, and adhesion to the matrix of the materials were characterized.@*RESULTS@#The GO/Ag3PO4 composites were successfully prepared by ion exchange method and the heterogeneous structure of GO/Ag3PO4 was proved by morphology phase test. The heterogeneous structure formed by Ag3PO4 and GO reduced the band gap from 1.79 eV to 1.39 eV which could be excited by 808 nm near-infrared light. The photothermal and photocatalytic experiments proved that the GO/Ag3PO4/CS coating had excellent photothermal and photodynamic properties. In vitro antibacterial experiments showed that the antibacterial rate of the GO/Ag3PO4/CS composite coating against Staphylococcus aureus reached 99.81% after 20 minutes irradiation with 808 nm near-infrared light. At the same time, the composite coating had excellent light stability, which could provide stable and sustained antibacterial effect.@*CONCLUSION@#GO/Ag3PO4/CS coating can be excited by 808 nm near infrared light to produce reactive oxygen species, which has excellent antibacterial activity under light.
Subject(s)
Chitosan , Silver Nitrate , Titanium , Anti-Bacterial Agents/pharmacology , Coloring AgentsABSTRACT
This paper presents a method of noninvasive and continuous measurement of blood pressure by pulse wave. The method is realized by extracting the characteristic parameters of human brachial artery pulse wave and developing the stepwise regression equation. The experiment results showed that blood pressure measured by this method was well correlated with which measured by mercury sphygmomanometer. The mean difference of blood pressure was smaller than 3 mmHg, and the standard deviation was smaller than 5 mmHg.
Subject(s)
Humans , Blood Pressure , Physiology , Blood Pressure Determination , Methods , Blood Pressure Monitors , PulseABSTRACT
With the electronic medical records information system as the core of hospital information platform design, this paper introduces the design of the system which is structured for electronic medical records, and the advantage and effectiveness is also introduced. From the aspects of the concept, system framework, data integration, right frame and safety control, identity index and a clinical pathway, etc, the paper introduces the basic idea and process of the hospital information platform design, with the hospital recording electronic medical records as the core.
Subject(s)
Electronic Health Records , Hospital Information Systems , Medical Records Systems, ComputerizedABSTRACT
In order to control real-time sampling and achieve smooth scroll wave in the epicardial mapping system, which has 128 channels and a sampling rate of 2kHz/channel, we have designed a user interface using Direct-Draw in cooperation with multiple-thread technology and extracting method. This method has proven to be feasible in animal experiment.