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1.
China Pharmacist ; (12): 602-603,615, 2015.
Article in Chinese | WPRIM | ID: wpr-671153

ABSTRACT

Objective:To observe the clinical effect of marzulene-S granules combined with phloroglucinol injections in the treat-ment of pregnant women with acute gastritis. Methods:Totally 102 cases of pregnant women with acute gastritis were randomly as-signed into two groups with 51 cases in each. The control group was treated with marzulene-S granules 30min before meals with warm water,0. 67g,tid,and the observation group was additionally given phloroglucinol injection 80 mg in 0. 9% sodium chloride injections 20ml,ivd,qd. The treatment course was 2 weeks. The clinical curative effect of the two groups was observed before and after the treat-ment,and the symptom score changes and symptom remission time were compared as well. Results:The effective rate of the observa-tion group was significantly higher than that of the control group(94. 12% vs 78. 43%,P<0. 05). After the treatment,the integral of epigastric pain,belching and dry mouth in the observation group was decreased significantly than that before the treatment(P<0. 05), and significantly lower than that in the control group(P<0. 05). The time of abdominal pain was(1. 8+0. 4)d and(3. 9+1. 1)d in the observation group and the control group,respectively,and the difference was statistically significant(P<0. 05). üo serious ad-verse reactions were found in the two groups. Conclusion:Marzulene-S granules combined with phloroglucinol injections in the treat-ment of pregnant women with acute gastritis is effective.

2.
China Modern Doctor ; (36): 8-10,15, 2015.
Article in Chinese | WPRIM | ID: wpr-1037363

ABSTRACT

Objective To investigate the prognosis value of pulmonary infection score and acute physiology and chronic health evaluation to acute exacerbation of COPD with type 2 respiratory failure. Methods 112 cases with acute exacer-bation of COPD with type 2 respiratory failure were selected as research subjects in our hospital from February 2011 to February 2014,scores of two scoring methods,actual mortality with different scores of two scoring methods,ROC curve predicted mortality of two scoring methods to chronic obstructive pulmonary disease with acute exacerbation of respira-tory failure of survival group and death group were compared. Results There were no significant differences between the two groups in PaO2、pH、PaCO2 and HCO3-(t=1.742, 1.647, 1.791, 1.082, P>0.05);but the levels of AG and poten-tial HCO3-in death group were higher than those in survival group(t=10.865, 5.993, P<0.05). APACHEⅢ,CPIS scores of survival group significantly were lower than the death group, the differences were statistically significant (t=6.254,4.397,P<0.05). Mortality of APACHⅢ score ≥25 and CPIS score ≥6 were significantly higher than patients with lower than that value, the differences were statistically significant(χ2=10.264,7.351,P<0.05). CPIS predict mortality acute exacerbation of COPD with type 2 respiratory failure, the area under the ROC curve was 0.867,APACHEⅢpredict mortality acute exacerbation of COPD with type 2 respiratory failure, the area under the ROC curve was 0.938. Conclusion CPIS and APACHEⅢ has certain prognostic value to acute exacerbation of COPD and type 2 respiratory failure,but APACHEⅢ resolution are better, it can provide a reference for disease prediction, it is worthy of applica-tion and promotion in clinical.

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