ABSTRACT
Purpose To investigate the topological structure differences between the migraine patients group and the normal control group by using resting-state brain complex networks constructed based on graph theory. Materials and Methods Resting-state functional magnetic resonance imaging dataset were obtained from 22 migraine patients and 22 normal subjects. The functional complex networks of the two groups were constructed, and parameters including average clustering coefficient, characteristic path length, small worldness, assortativity, and betweenness of the two groups were respectively calculated. Results When compared with the parameters of normal control group, average clustering coefficient of migraine patients group was larger, small worldness and assortativity were also changed. The characteristic path length of the caudate nucleus and putamen areas presented abnormal in the migraine patients group. Betweenness centrality of the thalamus, inferior occipital gyrus and occipital gyrus increased in the migraine patients group. Conclusion The abnormal brain regions in the migraine patients group were mainly associated with pain processing, visual processing and sensory information relay. This study may contribute to better understanding and interpreting corresponding clinical condition of migraine.
ABSTRACT
Objective:To study the biomechanical basis of swan like memory compressive connector (SMC) for treating fractures and nonunions of humerus. Methods:The study was performed by electrometric, two and three dimensional (3D) photoelasticity techniques. By gauging and multiple time standardization, load strain curve was got, then the dynamic memory force of SMC was calculated. The dynamically compressive force of swan neck compressive part was calculated by 2D photoelasticity. By precision moulding, the epoxy resin 3D photoelasticity humeral model was established, then it was fixated by SMC, meanwhile, an epoxy resin cirque was used to share the continuously memorial compress. The 3D stress distribution of humeral model was got, and 6 space component stress of the inspected node was divided by Leize polarizing microscope. Results:The continuously memory force of SMC was 110.35 N. The longitudinal dynamical compressive memory force was 163.88 N. 3D photoelasticity method showed that the swan neck compressive part of SMC, swan body connecting part of SMC and swan wing holding part of SMC were in consistent with each other, memorably holding bone, 3D fixation style was formed, and overall stress distribution was produced.. Conclusion:The stress field produced by 3D memory fixation of SMC is good for the treatment of fractures and nonunions. Early function exercises are allowed, and the fracture healing is prompted.