ABSTRACT
Objective To observe the effect of indwelling transanal tube on prevention of anastomotic leakage after congenital megacolon radical correction. Methods One hundred and three children who had underwent congenital megacolon radical correction were divided into indwelling group (53 cases) and no indwelling group (50 cases) according to the operation method, and the operation condition and incidence of complications was compared between 2 groups. Results There were no statistical differences in operation time, amount of bleeding during operation and incidence of other complications (pelvic infection and disruption of wound) (P>0.05). The incidence of anastomotic leakage in indwelling group was significantly lower than that in no indwelling group: 0 vs. 12.0% (6/50), and there was statistical difference (P<0.05). Conclusions Indwelling transanal tube for drainage and decompression is effective in preventing the anastomotic leakage after congenital megacolon radical correction, and it has high effectivity and safety.
ABSTRACT
Objective To investigate the feasibility and efficacy of tunica vaginalis flap cover in treatment of recurrent urethrocutaneous fistula (UCF).Methods We reviewed the clinical datas of 25 cases of UCF after urethroplasty of hypospadias from January 2011 to January 2015.The mean age of the patients was 6.2 years(range 1.6-14.0 years).All patients had undergone previous hypospadias repair and at least one previous failed attempt to close the urethrocutaneous fistulae.There were 5 cases of fistula in the coronary sulcus,6 cases of fistula in the penile body and 14 cases of fistula at the junction of penis and scrotum.The diameter of urethrocutaneous fistulae were 3-10 mm.Single fistula was present in all patients.16 cases had undergone UCF repair for two times, 9 cases had undergone UCF repair for more than two times.After closing the fistula with inverting running stitch, a tunica vaginalis flap was mobilized to cover the repair site through a subcutaneous tunnel and the skin closed.Results The mean follow-up time was 2.1 years(range 0.5-4 years).The overall success rate was 96％ (24/25).Penile cosmesis was excellent.There was no evidence of recurrent fistulas or urethral strictures.All parents reported a straight penis when erected, and one patient in whom there was leak from the fistula site because of local wound infection.No postoperative complication was encountered in the testis.The testis was of normal size and position, and the ultrasound findings were normal.Conclusions Repairment of recurrent urethrocutaneous fistulas with a tunica vaginalis flap could be effective regardless of fistula location.The technique is simple to improve the success rate of the repair of UCF effectively and reduce the occurrence of postoperative complications.
ABSTRACT
@#Objective To observe the changes of interleukin-1β (IL-1β) in spinal tissues of rats with acute spinal cord injury after electroacupuncture (EA) treatment, and its association with inflammatory reaction and apoptosis after spinal cord injury. Methods The spinal cord injury of all the rats was induced by a 10 g × 2.5 cm impact with the reformative Allen equipment. The IL-1β and caspase-3 in spinal nerves of rats were detected with immunohistochemistry, while the level of superoxide dismutase (SOD) and malondialdehyde (MDA) in spinal tissues with the Colourimetry, neuron apoptosis with the terminal deoxynucleotidyl transferase-mediated deoxyuredine triphosphate-biotin nick end labeling (TUNEL). Results At the end of EA therapy, the expression of IL-1β and caspase-3, the level of MDA, and the number of TUNEL positive cells in EA group were all significantly lower than those in the control group (P<0.01), and the activity of SOD was obviously higher (P<0.01). Conclusion The EA therapy can decrease the expression of IL-1β and caspase-3 in rats of acute spinal cord injury, and alleviate the inflammatory reaction and apoptosis after spinal cord injury.