ABSTRACT
Objective To explore the expression level and the clinical significance of Cys C,β2-MG,α1-MG in pediatric patients with congenital hydronephrosis.Methods 98 pediatric patients definitely diagnosed with congenital hydronephrosis in the depart-ment of pediatric surgery and urology of our hospital were enrolled and assigned to group B.The blood samples were collected.Ad-ditionally,selected another 98 normal children as a control:group A.Then the expression level of Cys C,β2-MG andα1-MG were de-tected via ELLSA for the groups.Results With aggravation of hydronephrosis,the expression of Cys C,β2-MG andα1-MG elevated correspondingly.Moreover,compared to the control group,the expression of Cys C,β2-MG andα1-MG in the pediatric patients with different degrees had significant differences(P 0.05).Conclusion Cys C,β2-MG and α1-MG can be used for evaluating the hydronephrosis and renal impair-ment.And it has more important significance by combining them.