Differentiation breast mass lesions between benign and malignancy by contrast-enhanced dynamic MRI classification / 中华放射学杂志

ObjectiveThe purpose of this paper is to grade hypervascularized mass lesions in CE MR imaging of the breast by analyzing morphology and dynamic characteristics.MethodsCriteria for the evaluation of breast MR findings were used,including the analysis of shape,margin,internal enhancement characteristics,initialenhancementphase,anddelayedphaseenhancementpattern.Atotalof 188 hypervascularized mass lesions were analyzed,and scores were given from 1 to 10 points and then the mass was classified into one of five categories.Next,the score results and pathology results were used to calculate the ROC curve and to find out the optimal benign and malignant diagnosis points.According to these results,the lesions were classified as benign or malignant.The sensitivity and specificity of this classification system were also calculated.ResultsOut of the 188 hypervascularized mass lesions,91 lesions were confirmed to be malignant by pathologic diagnosis and 97 to be benign.The area under the ROC curve was 0.938 ± 0.016.This curve was used to calculate the optimal point of differentiation diagnosis,and it was found to be a score of 5.The 188 lesions were classified into grade Ⅱ of 24 lesions,grade Ⅲ of 72,grade Ⅳ of 54,and grade Ⅴ of 38.Sensitivity for the detection of malignancy using this classification system was 87.91％ and specificity was 87.62％.If the three cases with false negative results of ductal carcinoma in situ of grade Ⅲ were excluded,the specificity increased to 90.90％.Conclusion The classification based on a multifactorial analysis is very helpful in the objective interpretation of breast CE MRI.

Investigation on diarrhea of 285 HIV/AIDS cases / 国际中医中药杂志

Objective To get overview about diarrhea condition of HIV/AIDS cases among paid blood donors in our country. Methods One-to-one questionnaire was adopted to investigate a total of 285 HIV/AIDS cases among paid blood donors in Henan province. Diarrhea HIV/AIDS patients were further picked out according to 'Criteria of HIV/AIDS diarrhea'and their syndrome characteristics were analyzed. Results There was 41 diarrhea HIV/AIDS patients in all 285 HIV/AIDS cases (14.39%). Deficiency Syndrome and mixed insufficiency and excess syndrome were predominant Syndromes in these patients. Conclusion The rate of diarrhea in HIV/AIDS cases among paid blood donors of our country was lower than some foreign countries. Such internal organs as spleen, liver, kidney, stomach and lung were mainly involved in the disease.

Female outlet obstruction constipation: assessment with MR defecography / 中华放射学杂志

Objective Using MR defecography to assess the morphological and functional anorectal anomalies related to female outlet obstruction constipation, and evaluate the joint disease of anterior and mid pelvic. Methods One hundred and seven female patients, aged 20 to 84 years ( average, 55 years), were diagnosed as outlet obstruction constipation based on clinical symptoms and signs. They all received MR defecography in our institution. The high compliance homemade balloon was inserted into rectum to simulate stool Then relevant measurements were obtained during rest, squeezing and straining, respectively. Results In all the 107 cases, 70 ( 65.4% ) presented rectocele on dynamic MRI; 28 ( 26. 2% ) presented anismus;60 (56. 1% ) presented cystocele; 59 presented vaginal or cervical prolapse(55. 1% ); and, 54 (50. 5% )presented descending perineum. In 85 females (79.4%) multiple disorders were detected, involving more than one pelvic compartment. Conclusion MR defecography allowed to accurately evaluate the morphological and functional anorectal anomalies related to female outlet obstruction constipation, and the joint disease of anterior and mid pelvic.