ABSTRACT
The effect of different doses of ulinastatin on cellular immunity and hepatorenal functions in patients undergoing laparoscopic colorectal-carcinoma surgery was observed and analyzed. The 200 patients with laparoscopic colorectal-carcinoma surgery in our hospital were selected as research subjects and divided into 4 groups containing equal patients, namely, saline group, 0.5 x 104U/kg ulinastatin group, 1 x 104U/kg ulinastatin group, and 1.5 x 104U/kg
ulinastatin group, which were denoted as group A, group B, group C and group D, respectively. The treatment effect of patients in 4groups was observed and compared. By observing the Narcotrend cerebral state index [NT index], the results showed that NT index at tracheal intubation, pneumoperitoneum beginning, pneumoperitoneum 30min, resection of tumor, end of operation in 4 groups was significantly lower than that at preoperative anesthesia [T0] [p<0.05];
differences in hepatorenal values [AST, ALT, BUN and Cr] among 4 groups at T0 were of no statistical significance [P > 0.05]; each index in T cell subsets in the postoperative third days [T1] was significantly lower than that at T0; indexes of T cell subgroup of group B, C and D at T1 were higher than that of group A at T1 [p<0.05]. For 4 groups, the difference in liver and kidney function indicators at T1 and T0 was of no statistical significance, p>0.05. Different doses of ulinastatin have a certain effect on cellular immunity in patients undergoing laparoscopic colorectal-carcinoma surgery and do not significantly affect hepatorenal function
ABSTRACT
Objective To Qingre ChuBi decoction combined with psychological intervention efficacy and safety in the treatment of patients with acute gout were analyzed. Methods In our hospital from March 2014 to November 2016 received 68 cases of acute gout patients as the research object, according to patients were randomly divided into control group and treatment group, 34 cases in the control group were treated with Etoricoxib Tablets and psychological intervention treatment, 34 cases of patients in the treatment group in the control group plus Chubi decoction for clearing. Results Two groups of patients before treatment VAS score were compared, no significant difference; The VAS score after treatment compared with before treatment were significantly decreased (P<0.05), comparison between groups had significant differences; compared with control group, VAS score improved more obviously (P<0.05), comparison between groups had significant differences. Conclusion Qingre ChuBi decoction combined with psychological intervention has a good effect on the treatment of acute gout, high safety, worthy of clinical application.