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São Paulo med. j ; 118(6): 201-3, Nov. 2000. ilus
Article in English | LILACS | ID: lil-277631

ABSTRACT

CONTEXT: One strategy for identifying susceptibility genes for common disorders is to investigate Mendelian diseases, cosegregating with these common disease phenotypes. CASE REPORT: A family with seven members is described, in which three members present Darier's disease and depression. This apparent cosegregation, if true, would support the hypothesis that in some pedigrees, a gene for mood disorder may be located on chromosome 12


Subject(s)
Humans , Male , Adult , Depression/genetics , Darier Disease/genetics , Chromosomes, Human, Pair 12/genetics , Mood Disorders/genetics , Genetic Predisposition to Disease , Chromosome Segregation/genetics , Darier Disease/complications , Darier Disease/psychology
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