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1.
Southeast Asian J Trop Med Public Health ; 1982 Mar; 13(1): 96-9
Article in English | IMSEAR | ID: sea-34529

ABSTRACT

The minimum inhibitory concentration (MIC) of penicillin, tetracycline and spectinomycin was determined for 6 beta-lactamase (PPNG) and 73 non beta-lactamase producing Neisseria gonorrhoeae isolates from Jakarta, Indonesia. All PPNG were resistant to greater than or equal to 128 micrograms/ml penicillin. Forty-six percent of the non-PPNG strains were inhibited by less than or equal to 1.0 microgram/ml of penicillin and 97% by less than or equal to 4 micrograms/ml. Most of the PPNG and non-PPNG isolates (90%) were inhibited by less than or equal to 4 micrograms/ml tetracycline and less than or equal to 16 micrograms/ml spectinomycin. Two non-PPNG strains were resistant to 64 micrograms/ml of tetracycline, 8 micrograms/ml penicillin and 32 micrograms/ml spectinomycin. The non-PPNG strains generally were more resistant to penicillin and tetracycline compared to strains tested from other parts of the world in previously reported studies.


Subject(s)
Anti-Bacterial Agents/pharmacology , Asia, Southeastern , Indonesia , Neisseria gonorrhoeae/drug effects , Penicillin Resistance , Penicillins/pharmacology , Spectinomycin/pharmacology , Tetracycline/pharmacology
2.
Southeast Asian J Trop Med Public Health ; 1981 Dec; 12(4): 536-8
Article in English | IMSEAR | ID: sea-31075

ABSTRACT

Neisseria gonorrhoeae was isolated from 14 out of 50 (28%) of one group and 35 out of 60 (58%) of a second group of females in different areas of Jakarta, Indonesia. four (7%) of the patients in the second group were infected with penicillinase producing Neisseria gonorrhoeae (PPNG). This may be the first reported isolation of PPNG in Indonesia.


Subject(s)
Female , Gonorrhea/epidemiology , Humans , Indonesia , Neisseria gonorrhoeae/enzymology , Penicillinase/analysis
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