T-Lymphocyte Fluctuation in Patients with Primary Intracranial Tumors

To determine the T-cell mediated immunological status in patients with brain tumors, the percentages of active and total T-lymphocytes forming rosettes with sheep erythrocytes, were measured in sixteen patients with primary intracranial tumors;six benign astrocytomas, four glioblastomas, one medulloblastoma, two craniopharyngiomas and three meningiomas. The percentages of active and total T-lymphocytes were significantly decreased in all glioblastomas and two among six astrocytomas, but normal in all meningiomas.