ABSTRACT
Clear cell hidradenoma (CCH) is a relatively rare benign tumor that shows differentiation toward the structure of an eccrine sweat gland. The tumor masses are composed of solid areas and tubular lamina. Cystic spaces are often present and on rare occasions they can be of considerable size. The cystic variant of CCH is referred as solid cystic hidradenoma. We present a case of cystic clear cell hidradenoma that occurred on the abdomen in a 42-year-old man. The tumor contained a solid tumor of CCH encircled by a large cystic space, and the cystic space was lined by two to four layers of epithelium.
Subject(s)
Adult , Humans , Abdomen , Acrospiroma , Epithelium , Sweat GlandsABSTRACT
Renal cell carcinoma (RCC) is well known for its frequent metastasis and particularly to the lungs, liver, bones and brain, but metastasis to the skin is rare. We report here on a case of metastatic RCC in a 73-year-old man who presented with a 1.5 cm sized, moist, beefy-red and exophytic nodule on the scalp. The lesion had grown rapidly for 2 months and it clinically mimicked granuloma pyogenicum. A skin biopsy revealed a solid mass composed of clear cells with clear cytoplasm and oval hyperchromatic nuclei, and they were arranged in an alveolar pattern. As skin metastasis from renal cell carcinoma signals widespread systemic metastasis and a poor prognosis, clinicians should conduct a careful inspection of the skin of a patient with RCC and they should also have a high index of suspicion for finding a primary internal organ malignancy in the RCC patients who present with a skin lesion.
Subject(s)
Aged , Humans , Biopsy , Brain , Carcinoma, Renal Cell , Cytoplasm , Granuloma , Granuloma, Pyogenic , Liver , Lung , Neoplasm Metastasis , Prognosis , Scalp , SkinABSTRACT
Trichloroethylene (TCE) is a chlorinated hydrocarbon that is widely used as a degreasing agent in industry. Systemic absorption of this chemical can result in neurological, hepatic and cutaneous toxicity. Several cutaneous manifestations of TCE-exposed patients have been reported, including Stevens Johnson syndrome, subcorneal pustular eruption and generalized pustular eruption. We report here on an unusual case of TCE hypersensitivity syndrome in a 38 year old man after occupational exposure to TCE.
Subject(s)
Humans , Absorption , Hypersensitivity , Occupational Exposure , Stevens-Johnson Syndrome , TrichloroethyleneABSTRACT
The dermal melanocytoses include a variety of pigment lesions that are formed from the aberrant development of the neural crest-derived melanocytes as they migrate through the dermis during embryogenesis. Neurocristic cutaneous hamartomas is one type of the dermal melanocytoses, which contain dermal melanocytic, neurosustentacular and fibrogenic components and can undergo malignant transformation. We describe a case of dermal melanocytosis showing features of neurocristic cutaneous hamartoma.
Subject(s)
Female , Pregnancy , Dermis , Embryonic Development , Hamartoma , MelanocytesABSTRACT
BACKGROUND: Despite numerous therapeutic methods (destructive surgery, topical application or systemic administration of various medicaments), the treatment of verruca plana still remains unsatisfactory and some novel remedies have been required. The authors noticed incidentally the clearance of verruca plana lesions in a patient who received itraconazole for tinea pedis. OBJECTIVE: The purpose of this study was to investigate the therapeutic effects of itraconazole for verruca plana. METHODS: The patients with verruca plana were treated with itraconazole (200 mg/day for adults, and 100 mg/day for children below 10 years of age) for 2 weeks. Assessment of clinical response and occurrence of the side effects were examined at weekly intervals. RESULTS: Of the 20 patients, 11 patients (55.0%) had either complete (40.0%) or partial clearance (15.0%) of verruca plana within 2 weeks of itraconazole therapy without severe adverse effects. No significant differences in therapeutic responses were found with regard to ages, sexes and duration of the diseases. CONCLUSION: This study demonstrates that oral itraconazole could be an effective and safe candidate in the treatment of verruca plana.
Subject(s)
Adult , Child , Humans , Itraconazole , Tinea , WartsABSTRACT
Trichorrhexis nodosa is the most common hair shaft anomaly in which there is a chemical or physical traumatic injury, characterized by the development of node-like swelling, fragility of the shaft and paint brush effect on the side of the fracture. We report two cases of trichorrhexis nodosa in 15-year-old girl and 16-year-old-boy, occurring as results of repetitive hot-comb straightener and excessive scratching. Scanning electroscopic findings are typical to trichorrhexis nodosa.
Subject(s)
Adolescent , Humans , Hair , PaintABSTRACT
White fibrous papulosis of the neck is a rare disorder, characterized by asymptomatic white papules that appear around neck in elderly people. The histopathologic findings showed thickened collagen bundles in the papillary to mid dermis. We report a case of white fibrous papulosis of the neck in a 53-year-old man.
Subject(s)
Aged , Humans , Middle Aged , Collagen , Dermis , NeckABSTRACT
A 35-year-old woman with advanced lung cancer, treated with intravenous docetaxel and paclitaxel, developed subungual abscesses and secondary onycholysis involving all the finger nails. Bacterial culture demonstrated the growth of Pseudomonas aeruginosa. We report a case of onycholysis and subungual abscesses in a patient treated with docetaxel and paclitaxel.
Subject(s)
Adult , Female , Humans , Abscess , Fingers , Lung Neoplasms , Onycholysis , Paclitaxel , Pseudomonas aeruginosaABSTRACT
Argyria is a rare skin discoloration caused by silver deposition. We report a case of generalized argyria caused by ingestion of silver solution in a 63-year-old man. He had diffuse slate gray discoloration of sun-exposed skin, prominent face, neck and V of the chest. The histopathologic findings showed brown black granules deposited in the basement membrane zone of eccrine glands, pilosebaceous units, arteriolar wall and dermal elastic fibers.
Subject(s)
Humans , Middle Aged , Argyria , Basement Membrane , Eating , Eccrine Glands , Elastic Tissue , Neck , Silver , Skin , ThoraxABSTRACT
Sebaceous hyperplasia is not a rare disorder and commonly develops on the face over the age of forty. The typical clinical manifestation is 2~3 mm sized, single or multiple, soft, protuberant, yellowish nodules with central umbilication. Histological examination reveals a group of mature sebaceous lobules and central sebaceous ducts. We describe an unusual case of a 28-year old female patient with grouped premature sebaceous hyperplasia. The lesions presented clinically as grouped, yellowish, umbilicated papules on the left cheek, and had developed at 10 years of age.
Subject(s)
Adult , Female , Humans , Cheek , HyperplasiaABSTRACT
We report a case of a 44 year-old man with porokeratosis of Mibelli, who presented with a 10 year history of a 1 cm diameter, well-circumscribed, erythematous, scaly patch with an elevated border on his glans penis. Histologic examination revealed a typical cornoid lamella and absence of an underlying granular layer. The localized type of porokeratosis of Mibelli is most commonly found on the limbs: however, the face, lips, mucosal surfaces, or genital area may instead be involved. We report a case of porokeratosis of Mibelli confined to the glans penis, a very rare site.
Subject(s)
Adult , Humans , Male , Extremities , Lip , Penis , PorokeratosisABSTRACT
A 59-year old man presented with a 0.5 x 0.3 cm-sized area of, pink-colored, dome-shaped papules on the paranasal area. There was no previous history of trauma to the area. Histopathologic diagnosis was consistent with eccrine poroma. We reported a case of eccrine poroma arising on the paranasal area, an unusual location for this condition.