ABSTRACT
Purpose@#This study investigated the effects of abdominal meridian massage on abdominal distention, abdominal pain, and bowel motility recovery after sedated colonoscopy. @*Methods@#This quasi-experimental study was conducted from July 29, 2019 to September 10, 2019. Participants who underwent sedated colonoscopy at a general hospital in B city were assigned to experimental and control groups (n=27 each). The experimental group received abdominal meridian massage for 10 minutes at five acupoints (cheonchu, jungwan, gwanwon, gihae, daehoeng) post-colonoscopy. As outcomes, abdominal distention (subjective sensation of abdominal bloating and abdominal circumference), abdominal pain, and recovery of bowel movement (time of return of bowel sounds and passing gas post-colonoscopy) were measured. Data were analyzed using the independent t-test, x2 test, Fisher's exact test, analysis of covariance (ANCOVA), and repeated-measures ANCOVA using SPSS for Windows version 25.0. @*Results@#Statistically significant between-group differences were found for subjective sensation of abdominal bloating (F=3.89, p<.024), abdominal circumference (F=11.05, p<.001), time of return of bowel sounds (x2=33.40, p<.001) and passing gas (x2=32.88, p<.001), but not abdominal pain. @*Conclusion@#Abdominal meridian massage reduced abdominal distention and was effective for the early return of bowel function. Therefore, abdominal meridian massage can be used as a nursing intervention for relieving abdominal discomfort post-colonoscopy.
ABSTRACT
BACKGROUND: Several lines of evidence suggest that host genetic factors influence the outcome of exposure to Mycobacterium tuberculosis. The aim of this study was to determine whether polymorphisms in interleukin-1beta (IL-1beta) and Interleukin-1 receptor antagonist (IL-1Ra) genes associate with the susceptibility or resistance to pulmonary tuberculosis in Korean. METHODS: IL-1beta and IL-1Ra gene polymorphism were investigated in 60 drug sensitive (DS) and 100 multidrug-resistant (MDR) pulmonary tuberculosis cases, and 96 healthy controls. IL-1beta-511/-31/+3954 and IL-1Ra genotype were determined by polymerase chain reaction. RESULTS: Allelic and genotypic frequencies of IL-1beta-511/-31/+3954 showed no significant difference in 3 groups. IL-1Ra allele 2 heterozygotes were less frequent in DS (p=0.03, OR=0.26, 95% CI 0.07 to 0.95) and MDR tuberculosis (p=0.008, OR=0.26, 95% CI 0.09 to 0.75) than controls, but there was no significant difference between DS and MDR tuberculosis (p=1.00). CONCLUSION: IL-1Ra allele 2 heterozygote may be associated with resistance to pulmonary tuberculosis in Korean. Further studies will be required to confirm whether these results are of biologic significance.