ABSTRACT
The frontal sinus is one of the four paranasal sinuses in humans, and knowledge of its anatomy is important when performing surgery involving the frontal bone or sinus. Although many studies have measured the frontal sinus using radiography and computed tomography (CT), few studies have evaluated by using three-dimensional (3D) analysis. The purpose of this study was to analyze the frontal sinus using 3D reconstruction analysis and determine the differences in linear and volumetric measurements between sexes, sides, and ages. The sample comprised 281 facial CT scans: 173 and 108 from males and females, respectively. The width, height, and length of each frontal sinus and total volume were all larger in males than in females. Almost all linear and volumetric measurements were larger in young adults than in older for both sexes, but not all of the differences were statistically significant. Linear and volumetric measurements were larger for males than females regardless of age group. There were no statistically significant differences between the right and left sides except the width in males. The size of the frontal sinus was strongly influenced by sex and age. The measurements reported here might be useful for improving surgical procedures involving the frontal sinus.
ABSTRACT
Frankfort horizontal line, the line passing through the orbitale and porion, is one of the most widely used intracranial landmarks in cephalometric analysis. This study investigated the use of the orbito-occipital line extending from the orbitale to the external occipital protuberance as a novel horizontal line of the skull for substituting the Frankfort horizontal line. We evaluated the reproducibility of the new landmark and measured the angle between the orbito-occipital line and the Frankfort line. This study was conducted on 170 facial computed tomography (CT) scans of living adults from the Department of Plastic Surgery. After three-dimensionally reconstructed images were obtained from facial CT, the porion, orbitale, and external occipital protuberance were indicated by two observers twice. The angles between the orbito-meatal line (inferior orbital rim to porion; the Frankfort line) and the orbito-occipital line (inferior orbital rim to external occipital protuberance) were measured. There was no significant intraobserver or interobserver bias. The overall angle between the Frankfort line and orbito-occipital line was –0.5°±2.2° (mean±standard deviation). There was no statistically significant difference among side and sex. This study demonstrated good reproducibility of a new landmark—the external occipital protuberance—tested to replace the porion. The orbito-occipital line is a reliable, reproducible, and easily identifiable line, and has potential as a novel standard horizontal line to replace or at least supplement the Frankfort line in anthropological studies and certain clinical applications.
ABSTRACT
Osteoporosis is a major disease in aged women, increasing the risk for fractures accompanied by changes in the microarchitecture. The aim of this study was to investigate the three-dimensional (3D) histomorphology of femur diaphysis in the animal model for postmenopausal osteoporosis. The cortical bone of femur diaphysis of the rat was serially sectioned at a thickness of 5 μm and evaluated age-associated changes of the intracortical (osteonal) canal networks three-dimensionally. Cortical microstructures of 10-month old rats were not affected by ovariectomy. Intracortical canal networks were radial toward endosteal aspect and frequently interconnected across the neighboring canals with short arciform and irregular canals reminiscent for resorption spaces in ovarectomized 16-month old rats, contrary to intact canals in 16-month old control rat. Increased proportion of the periosteal circumference lamella and deformed endosteal regions with rare cortical canals hampered reconstructive histomorphology in ovarectomized rats of 26 month age. We have shown that 3D reconstruction of rat femur of the aged model over 16-month old is suitable methods that evaluate and microstructural change of the intracortical canals and cortical bone porosity by estrogen depletion.
ABSTRACT
Osteoporosis is a major disease in aged women, increasing the risk for fractures accompanied by changes in the microarchitecture. The aim of this study was to investigate the three-dimensional (3D) histomorphology of femur diaphysis in the animal model for postmenopausal osteoporosis. The cortical bone of femur diaphysis of the rat was serially sectioned at a thickness of 5 μm and evaluated age-associated changes of the intracortical (osteonal) canal networks three-dimensionally. Cortical microstructures of 10-month old rats were not affected by ovariectomy. Intracortical canal networks were radial toward endosteal aspect and frequently interconnected across the neighboring canals with short arciform and irregular canals reminiscent for resorption spaces in ovarectomized 16-month old rats, contrary to intact canals in 16-month old control rat. Increased proportion of the periosteal circumference lamella and deformed endosteal regions with rare cortical canals hampered reconstructive histomorphology in ovarectomized rats of 26 month age. We have shown that 3D reconstruction of rat femur of the aged model over 16-month old is suitable methods that evaluate and microstructural change of the intracortical canals and cortical bone porosity by estrogen depletion.
ABSTRACT
Frankfort horizontal line, the line passing through the orbitale and porion, is one of the most widely used intracranial landmarks in cephalometric analysis. This study investigated the use of the orbito-occipital line extending from the orbitale to the external occipital protuberance as a novel horizontal line of the skull for substituting the Frankfort horizontal line. We evaluated the reproducibility of the new landmark and measured the angle between the orbito-occipital line and the Frankfort line. This study was conducted on 170 facial computed tomography (CT) scans of living adults from the Department of Plastic Surgery. After three-dimensionally reconstructed images were obtained from facial CT, the porion, orbitale, and external occipital protuberance were indicated by two observers twice. The angles between the orbito-meatal line (inferior orbital rim to porion; the Frankfort line) and the orbito-occipital line (inferior orbital rim to external occipital protuberance) were measured. There was no significant intraobserver or interobserver bias. The overall angle between the Frankfort line and orbito-occipital line was –0.5°±2.2° (mean±standard deviation). There was no statistically significant difference among side and sex. This study demonstrated good reproducibility of a new landmark—the external occipital protuberance—tested to replace the porion. The orbito-occipital line is a reliable, reproducible, and easily identifiable line, and has potential as a novel standard horizontal line to replace or at least supplement the Frankfort line in anthropological studies and certain clinical applications.
ABSTRACT
The aim of this study was to identify the three-dimensional topography of the sphenoid door jamb (SDJ) in the lateral orbital wall and to propose navigational guidelines for safe deep lateral decompression using surgical landmarks. The 120 orbits and SDJs of 60 subjects were three-dimensionally reconstructed using Mimics software. The mean volumes of the orbit and SDJ were 24.3 mm³ and 2.0 mm³, respectively. The mean distances from the lateral orbital margin (LOM) to the anterior and posterior margins of the SDJ were 13.2 and 36.3 mm, respectively. The mean distances from the superior orbital fissure to the LOM and to the posterior margin of the SDJ were 40.2 mm and 4.6 mm, respectively. The mean distances from the inferior orbital fissure (IOF) to the anterior and posterior margins of the SDJ were 3.8 mm and 20.5 mm, respectively. In the superior approach of the orbit, it can be predicted that the area up to 3 cm posterior from the LOM is safe, while 1 cm posterior from the safe zone could be a dangerous zone. In the inferior approach of the orbit, the safe area will be about 1 cm posterior from the anterior tip of the IOF, and the area up to 1 cm posterior from the safe zone should be approached with extreme care.
Subject(s)
Decompression , Graves Disease , OrbitABSTRACT
This study investigated the topographic relationships among the eyeball and four orbital margins with the aim of identifying the correlation between orbital geometry and eyeball protrusion in Koreans. Three-dimensional (3D) volume rendering of the face was performed using serial computed-tomography images of 141 Koreans, and several landmarks on the bony orbit and the cornea were directly marked on the 3D volumes. The anterior-posterior distances from the apex of the cornea to each orbital margin and between the orbital margins were measured in both eyes. The distances from the apex of the cornea to the superior, medial, inferior, and lateral orbital margins were 5.8, 5.8, 12.0, and 17.9 mm, respectively. Differences between sides were observed in all of the orbital margins, and the distances from the apex of the cornea to the superior and inferior orbital margins were significantly greater in females than in males. The anterior-posterior distance between the superior and inferior orbital margins did not differ significantly between males (6.3 mm) and females (6.2 mm). The data obtained in this study will be useful when developing practical guidelines applicable to forensic facial reconstruction and orbitofacial surgeries.
Subject(s)
Female , Humans , Male , Cornea , OrbitABSTRACT
The face is the most important for individual identification, which showed racial and regional differences. The aim of the present study was to investigate that how much highly locate the facial structures in the face. In total, 551 Korean young adult volunteers with no deformity or surgical history of the face (218 males and 333 females) were selected. Subjects were photographed while sitting and assuming a standard head position, such that the porion and inferior orbital margin were in the same horizontal plane (Frankfurt plane), and they were gazing forward. The total face height was measured vertically from trichion to gnathion. And total face height was divided three heights such as upper, mid, and lower face height. Total face height of male was larger about 6% than female. The ratio of lower face height about upper face height was calculated, it showed 55.7% in male and 50.3 in female. The face was classified into three sets including high-set, mid-set, and low-set according the ratio. The male face showed relatively high-set face, while female face showed relatively low-set face. The present study is the first study to investigate about high- or low-set face, and the result is useful data to identify characteristics of the east Asian population including Korean.
Subject(s)
Female , Humans , Male , Young Adult , Asian People , Congenital Abnormalities , Head , Orbit , VolunteersABSTRACT
The current model of compact bone is that of a system of Haversian (longitudinal) canals connected by Volkmann's (transverse) canals. Models based on either histology or microcomputed tomography do not accurately represent the morphologic detail and microstructure of this system, especially that of the canal networks and their spatial relationships. The aim of the present study was to demonstrate the morphologic pattern and network of the Haversian system and to compare endosteal and periosteal sides in rats using three-dimensional (3D) reconstruction. Ten Sprague-Dawley rats aged 8-10 weeks were used. The femurs were harvested from each rat and fixed, decalcified with 10% EDTA-2Na, serially sectioned at a thickness of 5 microm, and then stained with hematoxylin and eosin. The serial sections were reconstructed three-dimensionally using Reconstruct software. The Haversian canals in the endosteal region were found to be large, highly interconnected, irregular, and close to neighboring canals. In contrast, the canals in the periosteal region were straight and small. This combined application of 3D reconstruction and histology examinations to the Haversian system has confirmed its microstructure, showing a branched network pattern on the endosteal side but not on the periosteal side.
Subject(s)
Animals , Rats , Eosine Yellowish-(YS) , Femur , Haversian System , Hematoxylin , Rats, Sprague-Dawley , X-Ray MicrotomographyABSTRACT
The purposes of this study were therefore to characterize the degeneration and regeneration of nerves to the calf muscles after selective neurectomy, both macroscopically and microscopically, and to determine the incidence of such regeneration in a rabbit model. Seventy four New Zealand white rabbits were used. Selective neurectomy to the triceps surae muscles was performed, and the muscles were subsequently harvested and weighed 1-4 months postneurectomy. The gastrocnemius muscles were stained with Sihler's solution to enable the macroscopic observation of any nerve regeneration that may have occurred subsequent to neurectomy. The change in triceps surae muscle weight was measured along the time course of the experiment. After neurectomy, nerve degeneration was followed by regeneration in all cases. The weight of the triceps surae muscle decreased dramatically between completion of the neurectomy and 1 month postneurectomy, but increased thereafter. The nerve branches were weakly stained with Sihler's solution until 2 months postneurectomy, and then strongly stained after 3 months. The number of myelinated axons was decreased at 2 month after neurectomy compared to nonneurectomized controls, but then gradually increased thereafter. Although there are currently no reports on the incidence of recovery after calf reduction, it may be a very common occurrence in the clinical field based on our findings. The findings of this study provide fundamental anatomical and surgical information to aid planning and practice in calf-reduction surgery.
Subject(s)
Rabbits , Axons , Incidence , Muscle, Skeletal , Muscles , Myelin Sheath , Nerve Degeneration , Nerve Regeneration , RegenerationABSTRACT
The aim of this study was to analyze the difference of the measurements of mandible between young male and female using three dimensional reconstruction images derived from the facial bone CT images. Type classification of mandible was performed based on the angle of base of mandible and the angle of mandibular margin observed from the anterior view and the correlation among the measurement items was analyzed. One hundred-ninety five young adults facial CT were collected from the Konkuk University medical center (98 females, 97 males; mean age 25.9 years, range 18~38 years). Three dimensional images of the face were reconstructed using software from CT images of whole specimens. The angle of the base of the mandible, the angle of the mandibular margin, total length of mandibualr margin, and the height of mandibular symphysis were measured. All measurement items were larger and longer in male than female (P<0.05). Three types were classified according to the mandibular angle. In female, the subjects were evenly distributed among groups, but group I which had large mandibular angle was most common in male. The smaller the height of mandibular symphysis, the larger the angle of base of mandible or the angle of mandibular margin (P<0.05).
Subject(s)
Female , Humans , Male , Young Adult , Academic Medical Centers , Classification , Facial Bones , MandibleABSTRACT
The objective of this study is anthropometric analysis of nose and mid-face in Korean. This study was based on extensive sample size and variable measurement points. Total 3,000 healthy volunteers (18 to 79 years of age) were took two standardized photographs (frontal and lateral view). And 21 items were measured per person. Age groups were classified into three as young, middle-aged, and elderly. Average nasal length was around 4 cm and height was 5 cm. Female was 5~6% smaller than male. Facial width was 3.5 times larger than nasal length. Nasal length reduced by 5% as get older. Nasofrontal angle was 141degrees and nasolabial angle was 92degrees. Nasal width was 39mm and intercanthal distance was 35 mm. The significant age-related changes were eyeball depth (se-pu) and intercanthal distance. The characteristic senile change of male mid-face was downward deflection of soft tissue but female was soft tissue atrophy. The goal of augmentation rhinoplasty is not filling up sellion point depression but superior shifting of that point. Similarity between nasal length and width was another interesting finding of Korean nose. The results of this study will represent typical values of Korean nose and facilitate exact prediction of surgical results.
Subject(s)
Aged , Female , Humans , Male , Atrophy , Depression , Nose , Rhinoplasty , Sample SizeABSTRACT
Anatomy education using skull models has been widely performed for a long time and known that it is actually much convenient and economical. However, until now, most of skull models used in anatomy class are imported from the United State or Europe. Therefore, the models showed characteristics of Caucasian skulls, and had several differences from skulls of Koreans. Hence, we made a specific replica model of skull which have various Korean characteristics. We used Korean male skull (aged 50 years) without defect due to diseases or fractures. The silicon was poured over the skull in the cubic frame and hardened. We took out the skull from the silicon frame and poured the resin into the frame to duplicate the original skull. After defoamation and hardening the resin, the skull model was taken out of frame. And we modified defects which occurred during duplicated process and made detailed structures which unrevealed in real skull. After completion of the skull model, we measured ten items of anthropological characteristics of the Korean and American skull models and compared 9 categories of index. As a result, there were significant differences in length-breadth index, length-height index, frontozygomatic index, nasal index between the Korean and American skull models; As aforementioned, the skull model, compared to Caucasian skull models, had numerous distinctive Korean skull features and this model can be used for anatomy education in South Korea.
Subject(s)
Humans , Male , Europe , Republic of Korea , Silicon , SkullABSTRACT
Illustrations in almost all textbooks and atlases of anatomy normally show that the zygomatic arch (ZA) and coronoid process (CP) of the mandible overlap vertically. Their topographic relationship is important for plastic surgeons in various situations, such as restorations of ZA fractures. The present study investigated the topographic relationship between the ZA and CP of the mandible in three-dimensional models of Korean human cadavers. The topographic relationship was classified into three types: overlapped, tangential, and separate. The overlapped type was the most common, but the three types showed similar incidences in three-dimensional models. There were no lateral or sex differences according to the three types. The incidence of both sides showing the same type was 70.1%. In conclusion, the predominance of illustrations in almost all textbooks and atlases showing the overlapped type is misleading, since the other two types - where the CP of the mandible does not overlap the ZA - are almost as common.
Subject(s)
Humans , Cadaver , Incidence , Mandible , Sex Characteristics , ZygomaABSTRACT
Identification of an individual is the mainstay of forensic investigation. In the present study, criteria for sex determination were established using 111 adult Korean sternums (63 males and 48 females). They were analyzed using identification points (IPs) and limit points (LPs), as reported previously. Only three of the ten parameters measured-sternal body length, sternal length (i.e., manubrium+body), and sternal area-were useful for sex determination, with sternal length being the most useful. The IP of sternal length was 147 and 130 mm for males and females, respectively. Using this parameter, 53.9% of males and 37.5% of females could be sexed with 100% accuracy. The LP was 141 mm for both males and females; sex could be discriminated accurately using this parameter in 85.7% of males and 85.4% of females
Subject(s)
Adult , Female , Humans , Male , SternumABSTRACT
The present study involved a detailed investigation of 3 cases of bifid rib, focusing on anatomical features, and classified them into 2 types. The bifid ribs were in the right fourth rib of all 3 male cadavers. The upper intercostal spaces of the fourth bifid rib were considerably narrowed, whereas the lower intercostal spaces were widened. Although the size and shape of the bifid space between the upper and lower divisions of the bifid rib were different, the intercostal muscles were present in the bifid space in all cases. The third anterior intercostal artery from the internal thoracic artery supplied the bifid space in all cases. In 2 cases, the fourth intercostal nerve ran along the inferior margin of the fourth bifid rib and innervated the muscles of the bifid space. In the third case, there was another branch from the third intercostal nerve supplying the muscles of the bifid space as well as the fourth intercostal nerve. The bifid ribs are associated with other diseases or develop accidentally or sporadically. Knowledge of this malformation is needed for the differential diagnosis with other diseases, such as a chest wall tumor or costal fracture.
Subject(s)
Aged, 80 and over , Humans , Male , Middle Aged , Cadaver , Ribs/abnormalitiesABSTRACT
The mandible is the largest and strongest bone in the face. The mandible retains its structure better than other skeletons in the forensic and physical anthropologic field. It can be used to distinguish the ethnic groups, genders and ages. However, it is often discovered as a part, not complete form. Therefore, it would be needed that sex determination must be performed using a part of mandible. The purpose of the present study was to investigate the possibility for sex determination of the mandible focusing on the ramus in Korean. We examined 92 Korean mandibles (68 males and 24 females). The range of age was 16~92 years (mean 60 years). The mandibles were photographed from the both lateral sides at standard position. Nine angular and fifteen linear items were measured by the computer-based image analyzer. Statistical analyses were performed using the Microsoft Excel and SPSS 12.0 software. The vertical height of the coronoid process was greater than that of the condylar process in almost cases (81.6%) regardless of sex. Three angular (gonion-condylion posterior, coronion-condylion, coronion-condylion but passing gonion) and two linear (gonion-condylion, gonion-coronion) items had statistically significant difference between both sexes. Five variables were used in making a series of discriminant functions for which an accuracy of 86.6% was attained.
Subject(s)
Humans , Male , Ethnicity , Mandible , SkeletonABSTRACT
Recently, in most medical schools of Korea, the educational method of gross anatomy, the first subject in medical education, has changed in several directions such as integrated lecture or problem-based learning (PBL). Therefore, the time of the lecture was constrained to reduce. The name of the gross anatomy integrated with embryology changed to 'human body and development' in Konkuk university since 2006. In addition to the classical dissection practice, the 'dissection seminar' was introduced since 2006. It was a method of dissection practice that one group demonstrate the procedure of dissection and explains the structures of the predissected cadaver to other students about the assigned subject. The questionnaire about dissection seminar was performed after the anatomy course. The most common opinion about dissection seminar was 'interesting and helpful for studying anatomy'. The common answers about the attitude were 'very positive' and 'positive'. The affirmatives during dissection seminar were in depth study and improve in collaboration. The inconveniences or lacks were insufficient time to prepare, unfairness in difficulty between the subjects, and discord among group members. The propositions for development were requirement of sufficient preparation time, request of guideline, and consideration of other schedule. As a result of self-estimation about dissection seminar, the direction of the dissection seminar have been advancing with time, and students became more interested in studying anatomy. The most important thing for maintaining the dissection seminar is making proper plan such as avoidance of examination of another subject.
Subject(s)
Humans , Appointments and Schedules , Cadaver , Cooperative Behavior , Education, Medical , Korea , Problem-Based Learning , Surveys and Questionnaires , Schools, MedicalABSTRACT
PURPOSE: The objective of this study is anthropometric analysis of mouth and lower face of Korean. The relationship of soft-tissue to underlying bony structures determine the overall aesthetics of the face. The goal of aesthetic surgery of the face is to achieve the ideal normal and enhance the aging face. The purpose of present study was to determine the change of the morphology of the mouth and lower face based on soft-tissue landmarks according to age group to facilitate prediction during aesthetic surgery. METHODS: The standardized photographs of 2,018 healthy volunteers(18 to 79 years of age; 1,070 males, 948 females) were investigated. Age groups were classified into young, middle-aged, and elderly groups. Five and seven items were measured on frontal and lateral view photographs, respectively. Individual dimensions were compared in the three age groups and between males and females. RESULTS: The width of mouth is 4.5 times larger than that of philtrum. Most of measured data decreased with age. However, woman's lip width of the mouth somewhat increased from the young to elderly. The width of lower face is 2.5 times larger than mouth in young age group and increased slightly from the young to middle- aged and thereafter slightly decreased to elderly group. Upper lip was more higher than lower lip and male lip was more higher than female. But male and female lip height is similar at old age. CONCLUSION: Most of Koreans showed prominent lower face because of the development or protrusion of the mandible. And the descent of soft-tissue around the mouth was one of the significant characteristics of senile change. The posterior retrusion of the subnasal was an another characteristic. This study will help to elucidate the age-related dimensional differences of the human being and to provide useful information for clinical applications in oral and aesthetic surgery.
Subject(s)
Aged , Female , Humans , Male , Aging , Asian People , Esthetics , Lip , Mandible , MouthABSTRACT
This study was performed to investigate the morphometric changes of myenteric plexus and type 1 interstitial cells of Cajal (ICC-I) in regeneration process of small intestine transection. Sprague Dawley rats (200~250 g) were anesthetized with ether; then the full thickness of ileal wall were semitransected; and subsequent end-to-end anastomosis were performed by using 6-0 silk suture thread. Sham-operated rats, which only underwent the laparotomy, were used for control group. Experimental animals were sacrificed at 3 days, 7 days, 15 days, and 30 days after the operation. In each group myenteric plexus and ICC-Is were prepared by histochemical method (NADH-TR stain for myenteric plexus, ZIO stain for ICC-Is) and cell numbers were counted by image analyzer (Image plus pro-5.0, Media Cybermedics, USA). Degeneration of myenteric neurons and ICC-Is occurred simultaneously and it was similar in oral and anal to the site of transection. Degeneration effects were most prominent at 3 days and 7 days after intestinal transection. In myenteric plexus, many neurons had degenerated appearances and about 40% of them were lost. Most of ICC-Is had cytoplasmic vacuoles and 20~37% of the cells were lost. At 15 days after transection, there were no more degeneration in myenteric neurons (20~25% cell loss) and ICC-Is (20~13% cell loss). At 30 days after transection, numbers of myenteric neurons were not recovered as that of the control group. However numbers of ICC-Is were as similar as that of the control group. In conclusion, we confirmed that degeneration effects of intestinal transection are more severe in myenteric plexus than in ICC-Is, and recovery of cell loss occurs more slowly in myenteric plexus.