ABSTRACT
Objective:To observe the clinical efficacy of electroacupuncture (EA) combined with tuina for chronic tension-type headache (CTTH). Methods:A total of 97 CTTH cases were randomly allocated into an observation group (n=52) and a control group (n=45). Patients in the observation group were treated with EA plus tuina based on pattern identification, whereas patients in the control group were treated with oral amitriptyline and oryzanol. Patients in both groups were treated for 8 weeks. A follow-up was conducted 3 months after the treatment. The intensity, duration, and frequency of the headache were recorded and compared before and after the treatment. Additionally, the patients' psychological state and quality of life (QOL) were compared between the two groups. Results:There were intra-group statistically significant differences in headache intensity score, headache duration, and headache frequency after the treatment and during the follow-up compared with those before the treatment (allP0.05). The World Health Organization quality of life-BREF (WHOQOL-BREF) scores were significantly reduced in both groups after the treatment or during the follow-up (allP<0.05); and the scores in the observation group were significantly lower than those in the control group (allP<0.05) during the same time frame. The total effective rate was 88.0% in the observation group, versus 71.4% in the control group, showing a significant difference (P<0.05). Conclusion:EA combined with tuina can significantly decrease the frequency of chronic tension-type headache, alleviate headache intensity, shorten headache duration, and improve the patients' wellness. It is better than amitriptyline plus oryzanol.
ABSTRACT
Objective To study the effect of arsenic trioxide(As_2O_3) on reactive oxygen species(ROS) of human hepatocellular carcinoma cell(HCC) line.Methods The MTT method was used to evaluate the influence of As_2O_3 on proliferation of HCC.ROS was detected by flow cytometry.Results As_2O_3 could obviously decrease the proliferation rate of HCC cell line in dose-dependent and time-dependent manner.The analysis of flow cytometry showed As_2O_3 could obviously increase ROS in dose-dependent and time-dependent manner as well.Conclusion As_2O_3 can inhibit the proliferation of hepatic cell carcinoma SMMC-7721 cell line significantly,and the anti-tumours mechanism of arsenic trioxide may be that it could induce SMMC-7721 cell apoptosis by increasing ROS level.