ABSTRACT
Objective:To investigate the super selective transhepatic arterial embolization (TAE) for effects of cyst volume and liver function in patients with symptomatic polycystic liver disease (PLD), and provide a reliable basis for clinical diagnosis and treatment. Methods: 14 cases of symptomatic patients with PLD were selected from October 2014 to October 2015 in our hospital using super selective hepatic arterial embolization. The upper abdomen was performed CT scan one year after surgery, and the volume of patients with liver cyst was tested. We observed the changes of total volume of liver before TAE and postoperative kidney function, adverse reactions, and the improvements after four months’ follow-up.Results: The angiography for the 14 patients showed liver volume increased in different degrees. It also showed that blood supply was mainly hepatic artery wall branch. There were different sizes of liver round unstained area. There was consistent between CT examination and unstained area in polycystic liver swollen area. The difference of the total volume of the liver cyst was statistically significant in 14 cases of the patients with PLD before TAE treatment and after 12 months’ treatment (t=2.8627,P0.05). Compared with the preoperative, there was little effect on liver function by TAE. After 3 to 12 months, symptoms gradually improved and physical rating increased. The improvement rate was 100% after 12 months and the physical score was from 90 to 100 points. The embolism syndrome in 14 cases of patients gradually disappeared after 1 to 5 days, and five days later the symptoms disappeared. Conclusions: There is a significant effect for symptomatic polycystic liver patients with TAE. It can improve efficacy and reduce patient suffering with a low recurrence rate. It is worthy of clinical application.
ABSTRACT
Objective To investigate the clinical efficacy of entecavir combined with danshen dripping pill for the treatment of chronic hepatitis B with hepatic fibrosis. Methods A total of 46 cases of chronic hepatitis B with hepatic fibrosis in our hospital were randomly divided into control group and observation group. The control group were treated with entecavir. The observation group were treated with entecavir combined with danshen dripping pill.The HBV-DNA negative rate, serum fibrosis markers (Serum HA,LN,PCⅢ,CⅣ) before and after treatment of two groups were com-pared. Results The HBV-DNA negative rate of observation group was 95.7%, which was significantly higher than 65.2% of control group (P<0.05). The serum fibrosis markers of two groups before treatment had no significant differ-ence(P>0.05). Serum HA,LN,PCⅢ,CⅣlevels of observation group after treatment were significantly lower than control group(P<0.05). Conclusion Entecavir combined with danshen dripping pill treatment for chronic hepatitis B with hep-atic fibrosis has exact effect. It can effectively reduce inflammatory activity,improve microcirculation and slow fibrosis down. It’s worthy of clinical widely used.