ABSTRACT
Objective@#To investigate the association of the abnormal length of human Y chromosome with semen quality and the outcome of assisted reproductive technology (ART).@*METHODS@#Based on the karyotype, we assigned the patients undergoing ART to a normal control, a long Y chromosome (Y>18), and a short Y chromosome group (Y18 group showed a significantly lower incidence rate of asthenozoospermia (31.03% vs 8.33%, P 18 and Y0.05).@*CONCLUSIONS@#Short Y chromosome may affect spermatogenesis, but the length of Y chromosome does not negatively influence the outcome of ART.
Subject(s)
Female , Humans , Male , Pregnancy , Asthenozoospermia , Genetics , Azoospermia , Genetics , Chi-Square Distribution , Chromosomes, Human, Y , Karyotype , Karyotyping , Pregnancy Rate , Reproductive Techniques, Assisted , Semen , Semen Analysis , Reference Standards , Sex Chromosome Aberrations , Spermatogenesis , Treatment OutcomeABSTRACT
<p><b>OBJECTIVE</b>To observe the management results of hemangioma in infants and children.</p><p><b>METHODS</b>Forty-nine cases of hemangioma in infants and children managed from 1986 to 2004 were reviewed. During the management period, the incidence and first visit age and sex were recorded. The location and volume of the lesions were photographed and followed up at an interval of 3 to 12 months until the complete involution of the tumor. The treatment modalities used included local injection of prednisone in 16 cases, surgery in 6 cases, and the remaining 33 cases were observed without treatment.</p><p><b>RESULTS</b>Thirty-three cases receiving no treatment involuted naturally. The complete involution age was found from 9 months to 10 years with average age of 5.4 years. The cosmetic results after involution were good.</p><p><b>CONCLUSIONS</b>Most hemangiomas do not need treatment and can involute naturally. However, in cases with severe complications such as expansion, destruction and obstructive or congestive heart failure, treatment is indicated.</p>