ABSTRACT
Abstract: Suxamethonium chloride is a depolarizing muscle relaxant used in general anesthesia. In overdose, it causes adverse reactions such as bradycardia, arrhythmia, cardiac arrest, and death. The article reviews the progress on testing methods of suxamethonium chloride such as infrared spectroscopy, chemical color reaction, chemical titration, enzyme electrode, chromatography and mass spectrometry.
Subject(s)
Humans , Anesthesia, General , Arrhythmias, Cardiac/chemically induced , Biosensing Techniques , Bradycardia/chemically induced , Chromatography , Drug Overdose , Heart Arrest/chemically induced , Mass Spectrometry , Neuromuscular Depolarizing Agents/analysis , Spectrophotometry, Infrared , Succinylcholine/analysisABSTRACT
OBJECTIVE@#Based on a retrospective analysis of the drunk driving cases, to explore the drunk drivers' personnel composition, occurrence time and psychology.@*METHODS@#As a result of punishment of the drunk driving by criminal law for one year from May 1st, 2011 to April 30th, 2012, 91 drunk driving cases were statistically analyzed the easy-happening time of drunk driving, the drunk drivers' age, gender, occupational characteristics, domicile and psychological factors.@*RESULTS@#In 97 drunk driving cases, 26-40 years old, non-local domiciled and non-professional male drivers were prone to drunk driving at night from 22:00 to 5:00.@*CONCLUSION@#The behavior of drunk driving is relevant to time, age, genders and occupation. The psychological characteristics of most drivers are fluky, making-life-easy, competitive and peacockish.
Subject(s)
Adolescent , Adult , Female , Humans , Male , Middle Aged , Young Adult , Accidents, Traffic/statistics & numerical data , Age Distribution , Alcohol Drinking , Alcoholic Intoxication/psychology , Automobile Driving/psychology , China/epidemiology , Forensic Medicine , Risk Factors , Sex Distribution , Social Behavior , Time FactorsABSTRACT
Micellar liquid chromatography (MLC) is a reversed phase liquid chromatography with mobile phases containing surfactant above its critical micellar concentration (CMC). The basic mechanism and advantages of MLC in physicochemical analysis were reviewed, and its applications in analysis of drugs, barbiturates, benzodiazepines were chiefly introduced in this paper. MLC is a potential method to toxicological analysis due to strong selectivity, wide application scope and easy biological samples, etc.