ABSTRACT
The high morbidity and mortality of pulmonary carcinoma,especially in male patient,are still the unsolved problems. Recently,more and more reports showed that gene therapy could have potential application in the treatment of the disease. In this article,some progresses in the gene therapy of pulmonary carcinoma, such as tumor suppressor gene,drug sensitive gene,antisense gene,multi-drug resistance gene,immune gene as well as anti-angiogenesis gene, were discussed.
ABSTRACT
A Review Resistin, a new hormone found in the year 2001 and secreted by adipocytes, is related to type 2 diabetes and obesity. It brings some hope to solve the medical hamper of insulin resistance. The resistin discovery, molecule structure, function and expression, secretion regulation as well as gene polymorphism are reviewed in the article. [
ABSTRACT
Herpes simplex virus-I type thymidine kinase gene is a drug sensitivity gene. It is still not very clear about how it kills tumor cells, the article reviewed in short in a few aspects such as molecular structure of TK gene, TK enzyme,bystander effect,gap junction intercellular communication,cell apoptosis and phagocytosis,inflammation and immunity reaction, and the developing direction of TK gene.