ABSTRACT
Current reform of higher medical education focuses on curriculum integration and corresponding reconstruction of teaching system. Chongqing Medical University has carried out the reform of medical personnel training mode from basic to clinical, which has achieved certain results. Three aspects including teaching content, teaching methods and appraisal system of the urogenital system curriculum integration are introduced in the paper. In the teaching content, the parts related to urogenital system in basic subjects and clinical subjects are extracted and integrated. In the process of teaching implementation, a teaching team is set up across departments and multidisciplinary joint teaching is carried out. In order to arouse the enthusiasm of students, inspire and cultivate students' scientific research thinking by improving teaching methods, several teaching methods such as case introduction teaching method, question discussion and debate meeting are used. Scientific evaluation system is used to observe and record the whole process of students' learning. Meanwhile, some existing problems and solutions of curriculum integration are discussed in the paper to provide references for peers in relevant colleges and universities.
ABSTRACT
Objective To evaluate application value of ultrasound elastography combined ultrasound and breast BIRADS classification in the diagnosis of breast cancer. Methods A total of 146 cases of breast lumps were treated with ultrasound elastography breast examination to pathological results as the gold standard,respectively elastic strain rate ratio, elastography score, BIRADS classification and joint benign and malignant breast masses were evaluated to compare diagnostic value of different diagnostic methods. Results The ratio of elastic strain rate of breast cancer diagnosis sensitivity,specificity and accuracy were 83.54%,89.89%,86.90%; elastography score diagnosis of breast cancer sensitivity,specificity and accuracy were 87.34%,92.26%,92.86%; BIRADS classification of breast cancer diagnostic sensitivity, specificity and accuracy were 88.61%,92.13%,90.48%; NO.1 two-linking diagnosis of breast cancer sensitivity,specificity and accuracy were 92.41%,93.26%,92.86%;NO.2 two-linking diagnosis of breast cancer sensitivity,specificity and accuracy were 89.87%,92.13%,91.07%;NO.3 two-linking bivalent three diagnostic sensitivity,specificity and accuracy were 93.67%,93.26%,93.45%;triple diagnosis of breast cancer sensitivity, specificity and accuracy were 96.63%,95.51%,95.83%. Bivalent a law,two French and three triple-linked increase in sensitivity,specificity and accuracy triple law had improved significantly(P<0 . 05). Triple Youden index and Kappa values were the highest,followed by two 3-linking method. Conclusion Ultrasound elastography and ultrasound BIRADS evaluation methods in the diagnosis of breast cancer classification has certain limitations, including two joint evaluation method can improve the sensitivity to a certain extent, but only the elastic strain rate ratio, elastography score,BIRADS classification can provide significant time and triple evaluate the sensitivity,specificity,accuracy,Youden index and Kappa values,has a high value.
ABSTRACT
Objective: To study the chemical structure of polysaccharide CDP 4 isolated from Cistanche deserticola Y.C.Ma. Methods: The chemical properties of CDP 4 were determined by using chemical method and spectrocospic method. Results: CDP 4 was composed of glucosyl group, with the ratio 1,4 linkage glc p ∶1,6 linkage glc p =3∶1,and its mean molecular weight 1.4 ?10 4. By means of methlylation analysis, complete acid hydrolysis analysis, NMR spectrum, the linkages and sequence information of CDP 4 were obtained. Conclusion: CDP 4 is a new linear glucan.