ABSTRACT
In response to the problem that the traditional lower limb rehabilitation scale assessment method is time-consuming and difficult to use in exoskeleton rehabilitation training, this paper proposes a quantitative assessment method for lower limb walking ability based on lower limb exoskeleton robot training with multimodal synergistic information fusion. The method significantly improves the efficiency and reliability of the rehabilitation assessment process by introducing quantitative synergistic indicators fusing electrophysiological and kinematic level information. First, electromyographic and kinematic data of the lower extremity were collected from subjects trained to walk wearing an exoskeleton. Then, based on muscle synergy theory, a synergistic quantification algorithm was used to construct synergistic index features of electromyography and kinematics. Finally, the electrophysiological and kinematic level information was fused to build a modal feature fusion model and output the lower limb motor function score. The experimental results showed that the correlation coefficients of the constructed synergistic features of electromyography and kinematics with the clinical scale were 0.799 and 0.825, respectively. The results of the fused synergistic features in the K-nearest neighbor (KNN) model yielded higher correlation coefficients ( r = 0.921, P < 0.01). This method can modify the rehabilitation training mode of the exoskeleton robot according to the assessment results, which provides a basis for the synchronized assessment-training mode of "human in the loop" and provides a potential method for remote rehabilitation training and assessment of the lower extremity.
Subject(s)
Humans , Exoskeleton Device , Reproducibility of Results , Walking/physiology , Lower Extremity , Algorithms , Stroke Rehabilitation/methodsABSTRACT
With the development of photothermal nanomaterials, photothermal therapy based on near-infrared light excitation shows great potential for the bacterial infected wound treatment. At the same time, in order to improve the photothermal antibacterial effect of wound infection and reduce the damage of high temperature and heat to healthy tissue, the targeted bacteria strategy has been gradually applied in wound photothermal therapy. In this paper, several commonly used photothermal nanomaterials as well as their targeted bacterial strategies were introduced, and then their applications in photothermal antibacterial therapy, especially in bacterial infected wounds were described. Besides, the challenges of targeted photothermal antibacterial therapy in the wound healing application were analyzed, and the development of photothermal materials with targeted antibacterial property has prospected in order to provide a new idea for wound photothermal therapy.
Subject(s)
Humans , Anti-Bacterial Agents/pharmacology , Nanostructures/therapeutic use , Staphylococcus aureus , Wound Healing , Wound Infection/therapyABSTRACT
@#Objective To evaluate the therapeutic effects of electromyography feedback functional electrical stimulation (FES) on plantar pressure of stroke patients. Methods 18 subjects were included in this study, who were with drop foot resulting from stroke, but could partly dorsiflex the paretic limb's ankle (Manual Muscle Test >2). They were tested on the RS-footscan plate before and after stimulation. The plantar pressure data of paretic foot and walking velocity before and after stimulation were compared. Results The initial touchdown points of most paretic foot were changed from Meta (metatarsal) 5 to heel; the time of initial touchdown of heel medial and heel lateral significantly improved, while that of Meta 3, Meta 4 and Meta 5 significantly delayed; the peak force, impulse and contact area of the heel significantly improved after stimulation (P<0.05). At the same time, the time of initial touchdown of heel medial and heel lateral of nonparetic foot significantly improved (P<0.05). Conclusion Electromyography feedback functional electrical stimulation can improve the gait pattern and the stability of patients with stroke.
ABSTRACT
Objective To evaluate the therapeutic effects of electromyography feedback functional electrical stimulation (FES) on plan-tar pressure of stroke patients. Methods 18 subjects were included in this study, who were with drop foot resulting from stroke, but could partly dorsiflex the paretic limb's ankle (Manual Muscle Test>2). They were tested on the RS-footscan plate before and after stimulation. The plantar pressure data of paretic foot and walking velocity before and after stimulation were compared. Results The initial touchdown points of most paretic foot were changed from Meta (metatarsal) 5 to heel;the time of initial touchdown of heel medial and heel lateral sig-nificantly improved, while that of Meta 3, Meta 4 and Meta 5 significantly delayed;the peak force, impulse and contact area of the heel sig-nificantly improved after stimulation (P<0.05). At the same time, the time of initial touchdown of heel medial and heel lateral of nonparetic foot significantly improved (P<0.05). Conclusion Electromyography feedback functional electrical stimulation can improve the gait pattern and the stability of patients with stroke.
ABSTRACT
Objective To compare the characteristics of plantar pressure between old and young people walking on flat. Methods 30 per-sons aged 55-65 years and 30 students aged 18-23 years were measured with a kind of plantar pressure measurement Footscan when they walked naturally, including impulse, max force, load rate of 10 regions, and distribution of the contact area of medial and lateral heels. Re-sults The impulse was significantly different in 7 regions between both sides in the old people, and in 3 regions in the students. The impulse was significantly less in the old people than in the students (P0.05). Conclusion The impulse, max force, load rate de-crease in the old people with the imbalance of distribution of the pressure between left and right.
ABSTRACT
@#Objective To compare the characteristics of plantar pressure between old and young people walking on flat. Methods 30 persons aged 55-65 years and 30 students aged 18-23 years were measured with a kind of plantar pressure measurement Footscan when they walked naturally, including impulse, max force, load rate of 10 regions, and distribution of the contact area of medial and lateral heels. Results The impulse was significantly different in 7 regions between both sides in the old people, and in 3 regions in the students. The impulse was significantly less in the old people than in the students (P<0.05). The max force was significantly different in 6 regions between both sides in the old people, and in 3 regions in the students. The max force was significantly less in the old people than in the students (P<0.05). The load rate was significantly different in 7 regions between both sides in old people, and in 3 regions in students. The load rate was significantly less in the old people than in the students (P<0.05). The contact area was larger in the medial heel than the lateral heel in old people group (P<0.05), and it was different between left and right foot. While the contact area was smaller in the medial heel than the lateral heel in the students (P<0.05), and there was no difference between left and right foot (P>0.05). Conclusion The impulse, max force, load rate decrease in the old people with the imbalance of distribution of the pressure between left and right.
ABSTRACT
Objective: To explore the effects of multivitamin and mineral supplements on self-evaluation of mood and health status in healthy volunteers.Methods:149 healthy volunteers took multi-nutrient supplements or placeboes for 8 weeks, and self-evaluation of mood and health status was evaluated by Profile of Mood States and 36-item short-form health survey.Results:Self-comparing POMS scores, active group's scores of vigor were significantly increased, from 14.2? 4.6 to 15.5 ? 4.9(t=2.74,P37)were significantly improved. But the placebo group and young volunteers were not significantly improved. Conclusion: The intervention of multivitamin and mineral supplements can improve elderly healthy persons' mood and healthy status.