Metrological Analysis of the Projects in the Field of Forensic Science Funded by the National Natural Science Foundation of China between 2000 and 2019 / 法医学杂志

Objective To understand the trend of funding in the field of forensic science by analyzing the projects funded by the National Natural Science Foundation of China （NSFC）. Methods Based on the data of funded projects in the field of forensic science published on NSFC website in the twenty years from 2000 to 2019, the trend of project number and fund, project type, discipline type, funded institution and personnel were analyzed with metrological methods. The funding theme was analyzed through multi-methods. Results In the twenty years, NSFC funded 352 projects in the field of forensic science, including 9 project types, 47 institutions and 213 persons. General programs （184 projects）, forensic toxicology, pathology, and toxicology analysis （H2301, 188 projects）, and the Academy of Forensic Science （37 projects） had the most funded projects. NSFC funded 174.69 million yuan in the field of forensic science. The Excellent Young Scientists Fund （3.50 million yuan/project）, forensic toxicology, pathology, and toxicology analysis （H2301, 78.64 million yuan）, and Xi'an Jiaotong University （23.78 million yuan） had the most funding. The differences in the number and funding of subsidized projects between the first ten years and the last ten years had statistical significance （P<0.05）. The main targets of funding were toxicology research, evidence-related research, estimation-related research, brain injury research, et al. The field of research mainly funded from 2010 to 2019 was interdisciplinary research. Conclusion Since 2010, the number of project, funding of project, the number of institutions and persons funded by NSFC in the field of forensic science showed an increasing trend. The types of disciplines, types of projects and themes of projects are more diverse, which will promote the long-term development of basic forensic research in China.

Evaluation and Countermeasures of the Implementation of Forensic Clinical Identification Standards Based on the Perspective of Accreditation / 法医学杂志

The new Standardization Law, implemented in 2018, has added a standard post-implementation evaluation system, aiming to continuously improve the quality of standards through post-implementation evaluation. Standards in the forensic science field are closely related to accreditation activities. Forensic science standards are not only the criteria on which accreditation activities are carried out, but also one of the key contents of the inspection of forensic science institutions in accreditation activities. Since 2018, the certification and accreditation policies in the forensic science field have also been changed, which has brought impacts on the construction of a standard system based on accreditation.This paper analyzes the standard data from China National Accreditation Center from Conformity Assessment on forensic clinical identification accreditation assessment. It points out that the current coverage of laboratory accreditation activities is limited, the development in different provinces is unbalanced, and there is overlap and crossover in the standards in use. It is emphasized that the construction of the national forensic science standardization technical committee, the improvement of the forensic science standard system, the establishment of the standard implementation evaluation index system, and promotion of the coordination of standards, and the certifications and accreditations should be accelerated, in order to continue to promote the standardization and accreditation activities in the field of forensic science.

Influence of dexmedetomidine on coronary artery and myocardial protection in AMI patients undergoing PCI / 心血管康复医学杂志

Objective :To explore influence of dexmedetomidine (DEX) on coronary artery diameter and myocardial protection in patients with AMI undergoing PCI .Methods :A total of 92 AMI patients ,who received PCI in our hospital from Mar 2016 to Mar 2017 ,were selected .Patients were randomly and equally divided into routine PCI group and DEX group (received DEX intravenous pump based on routine PCI group ).Coronary artery diameter , HR ,SBP ,DBP ,serum levels of cardiac troponin I (cTnI) ,heart type fatty acid-binding protein (H-FABP) and creatine kinase isoenzyme MB (CK-MB) before ,6h and 24h after treatment ,and incidence of adverse reactions were observed and compared between two groups .Results :Compared with routine PCI group ,on 6h and 24h after treatment ,there were significant reductions in coronary artery diameter [24h : (2.68 ± 0.36) mm vs .(2.44 ± 0.35) mm] , HR [24h :(86.56 ± 8.12) beats/min vs .(75.42 ± 7.05) beats/min] ,DBP [24h :(76.26 ± 10.30) mmHgvs.(68.28 ± 9.25) mmHg] and SBP [24h :(133.17 ± 23.76) mmHg vs.(118.28 ± 10.26) mmHg] in DEX group , P＜0. 01 all.Compared with before treatment group ,there were significant rise respectively in serum levels of cTnI and CK-MB in two groups on 6h and 24h after treatment ,and serum H-FABP levels significantly decreased respectively , P＝0.001 all.Compared with routine PCI group ,on 6h and 24h after treatment ,there were signifi-cant rise in serum levels of cTnI [24h :(1.23 ± 0.05) ng/mlvs.(1.64 ± 0.07) ng/ml] and CK-MB [24h : (125.09 ± 13.16) μg/ml vs.(149.71 ± 14.53) μg/ml] ,and significant reduction in serum H-FABP level [24h : (10.44 ± 2.59) ng/ml vs.(8.31 ± 2.16) ng/ml] in DEX group , P＝0.001 all.Incidence rate of adverse reactions in DEX group was significantly lower than that of routine PCI group (6.52% vs.23.91%) , P＝0. 020. Conclusion : Though dexmedetomidine can constrict coronary artery ,but it can perform myocardial protection through reducing blood pressure and HR etc .in AMI patients undergoing PCI ,and its adverse reactions are few ,which is worth extending .