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Journal of Experimental Hematology ; (6): 1478-1484, 2021.
Article in Chinese | WPRIM | ID: wpr-922282

ABSTRACT

OBJECTIVE@#To investigate the toxic damage and possible mechanism of chronic exposure of ambient particulate matter (PM@*METHODS@#Mice were treated with different doses (150, 300, 600 mg/kg) of chitosan after exposure to PM@*RESULTS@#Compared with the mice in control group, IL-2 secretion and CXCL12 expression were decreased in the bone marrow of PM@*CONCLUSION@#Chronic exposure of PM


Subject(s)
Animals , Mice , Bone Marrow , Chitosan , Hematopoietic Stem Cell Transplantation , Hematopoietic System , Particulate Matter/toxicity
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