ABSTRACT
Objective To study the effects of Glycyrrhiza polysaccharide (GP) on immune function in mice. Methods Polysacchayide was extracted from Glycyrrhiza uralensis by water-extraction-alcohol-precipitation method. Ovalbumin was injected to mice as antigens. The mice were randomly divided into four group:low (50 mg/kg), middle (100 mg/kg), high (200 mg/kg) dosage group of GP and normal control group, 12 mice in each group. Four groups were given GP and NS orally for seven days. After the secondary immunization, the level of antibody and the concentration of serum IFN-? were determined. Results The levels of antibodies and cytokines in middle and low dosage group of GP were all significantly higher than those of control group. Conclusion GP could enhance the immune function of mice.
ABSTRACT
Objective To evaluate the atherosclerotic and its risk factors in uremia patients with treated with hemodialy- sis.Methods the 30 cases of MHD patients and 21 health controls were chosen,the colour doppler's examination in neck atreria,serum CRP,,TNF-?,serum glucose,albumin and the calcium times phorphorus were analysed.Re- sults the IMT index,the level of CRP,TNF-?and Ca * P were higher in patients group than those of in control group,the level of albumin in patients group was decreased significantly and the level of Glu was not difference.Con- clusion the arteriosclerosis in uremia patients is related to the infections and nutrition status,the later is the risk factor of the former.