ABSTRACT
Objective:To explore the value of multiparametric ultrasonography consisting of gray-scale ultrasound(US), color Doppler flow imaging (CDFI), real-time strain elastography(RTE), and contrast-enhanced ultrasound(CEUS) in the differential diagnosis of testicular lesions.Methods:Forty patients (40 lesions) detected by ultrasonography examination at the Ultrasound Medical Center of Lanzhou University Second Hospital from June 2020 to June 2022 were retrospectively analyzed, and further the CDFI, CEUS and RTE were performed. The presence of vascularization in the lesion was determined by CDFI and CEUS, avascular lesions were defined as benign, vascularization lesions were defined as malignant. The lesion tissue elasticity was assessed by real-time strain elastography, tissue stiffness was encoded as red(soft), green(intermediate), and blue(hard), and the hard lesions were defined as malignant, soft lesions were defined as benign. All lesions were subjected to pathological histologic examination after surgical resection or puncture biopsy as a reference standard. The correct classification rate, sensitivity, specificity and likelihood ratio of the multiparametric ultrasonography imaging for the diagnosis of benign and malignant testicular lesions were analyzed by ROC.Results:Of 40 testicular lesions, 24 (60.0%) were benign and 16 (40.0%) were malignant. The sensitivity of CDFI, CEUS and RTE in the diagnosis of testicular lesions was 0.875, 1.000 and 1.000, and the specificity was 0.833, 0.750 and 0.708, respectively. The correct classification rate was 85.0%, 85.0% and 82.5%, and the positive likelihood ratio was 5.24, 4.00 and 4.42, respectively. AUC was 0.781, 0.802, 0.771, respectively. By combining RTE and CDFI, a sensitivity of 1.000 and specificity of 0.875 and correct classification rate of 92.8% and positive likelihood ratio of 8.00 and AUC of 0.915 ( P<0.001) were achieved in differentiating testicular lesions. And combining RTE and CEUS, achieved sensitivity of 1.000 and specificity of 0.917 and correct classification rate of 95.0% and positive likelihood ratio of 12.0 and AUC of 0.958( P<0.001). Conclusions:Multiparametric US is of great value in the differential diagnosis of benign and malignant testicular lesions.
ABSTRACT
Through summarizing and analyzing the characteristics of elderly infertile people,the problems emer-ging in the assisted reproduction process and the possible ethical problems emerging in the assisted reproduction treatment of elderly patients,this paper explored how to build the ethical path which aimed at elderly pregnancy -assisted people and suitable for Reproductive Center in the First Affiliated Hospital of Xinjiang Medical University. And aiming at the possible ethical problems emerging in the process of assisted reproduction treatment of elderly pa-tients,this paper put forward that it should establish normative ethical working path,to be more convenient to fully conduct ethical supervision and examination in the process of assisted reproduction treatment of elderly patients.
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Objective To evaluate the prevalence and associated risk factors of stress urinary incontinence (SUI) in adult women in Xinjiang.Methods In the cross-sectional study,3403 Uygur women aged over 20 years were interviewed through a questionnaire of International Consuhation on Incontinence Questionnaire Female Lower Urinary Tract Symptoms Module (ICIQ-FLUTS) and the adult questionnaire were used in our research.All parts of the content were according to the characteristics of women in Xinjiang and the purpose of our research.The risk factors were studied by Logistic regression analysis.Results The prevalence of urinary incontinence (UI) was 4l.96％ (1428/3403) and 28.21％ (960/3403) of SUI in Uygur women.In multivariate logistic regression analysis,the risk factors of SUI are body mass index (OR =1.672,95％ CI:1.082-2.584),parity (OR =5.092,95％ CI:3.889-6.666),neonatal birth weight (OR =5.623,95 ％ CI:3.335-9.480),the mode of delivery (OR =2.247,95 ％ CI:1.634-3.090),the lateral episiotomy (OR =4.448,95％ CI:3.112-6.357),menopause (OR =5.145,95％ CI:3.613-7.328),chronic pelvic pain (OR =3.869,95％ CI:1.051-14.250),pelvic organ prolapse (OR =3.501,95％ CI:2.508-4.887).Conclusion The incidence of SUI is related with multiple factors,especially with obesity and the obstetric factor.