ABSTRACT
Objective To improve microbial specimen detection rate before therapeutic antimicrobial use.Methods A system of selective targeted management by clinical department was established,before management was as control group (July-September 2013),after management was as intervention group(October-December 2013),microbial specimen detec-tion in patients before antimicrobial use was compared between before and after management.Results Of all hospitalized pa-tients,11 254 received therapeutic antimicrobial agents,3 426 were sent specimens for microbial detection,the specimen detection rate was 30.44%;specimen detection rate in control and intervention group was 28.80% and 31.89% respective-ly ,the difference was significant(χ2 =12.71,P <0.05).3 716 patients(46.61%)received restrained antimicrobial therapy, and 1 418 (79.20%)received special antimicrobial therapy,compared with control group,the difference were both signifi-cant(χ2 =32.86,19.31,respectively,both P <0.05).Conclusion Applying selective targeted management can improve microbial specimen detection rate before therapeutic use of antimicrobial agents.
ABSTRACT
OBJECTIVE To survey the drug resistance variation of pathogens.METHODS We analyzed all of the pathogens isolated from Jan 1998 to Dec 2005 and the drug resistance results.WHONET5 software was used to analyze the data.RESULTS A total of 19 832 strains of pathogens were detected for eight years.There was ascending tendency in ESBLs and MRS.The ratio of strains and resistance also varied.The general trend was that the order of Staphylococcus was going up and the order of non-fermented and fermented bacteria was ascending alternately.CONCLUSIONS The resistance variation of pathogens in our hospital consists with the global tendency of bacteria resistance.Of course it has its own characteristics.The resistance surveillance should be continued especially for ESBLs,MRS,VISA and VRSA.