ABSTRACT
Objective To understand the radioactivity level of food surrounding a uranium mine in Xinjiang, to supplement the baseline database of food radionuclides in Xinjiang, to analyze the content of radionuclides and to estimate the internal exposure dose of residents caused by dietary intake. Methods The specific activity of 238U, 232Th, 226Ra, 40K and 137Cs of interest nuclides was measured, statistically analyzed by high purity germanium γ spectrometer, and the annual effective dose of these nuclides was estimated. Results No nuclide 238U was detected in food samples from 2018 to 2020. The average activity concentration and detection rate of other radionuclides were 232Th: 0.428 ± 0.038 Bq/kg (18.3%)、226Ra: 0.477 ± 0.063 Bq/kg (38%)、40K: 162 ± 7 Bq/kg (100%)、137Cs: 0.071 ± 0.011 Bq/kg (29.6%). The annual effective dose of residents due to food radionuclides was about 0.198 mSv. Conclusion The radioactivity level of food in the vicinity of a uranium mining mountain in Xinjiang is within the national standard limit, and the average annual effective dose caused by the diet of residents is consistent with the report of UNSCEAR in 2000. The content of artificial radionuclide 137Cs detected in food samples will not cause harm to the health of residents.
ABSTRACT
Objective@#To explore the effects of teach-back on health education for patients′ gestational diabetes mellitus.@*Methods@#A total of 90 pregnant women with gestational diabetes mellitus from obstetrics outpatient were recruited and randomly assigned to either case or control group. The case and control groups received the same treatment and health education, the only difference was teach-back method in the case group,to compare blood glucose, compliance and outcome of pregnancy.@*Results@#After the intervention, fasting blood glucose (FPG), 2h postprandial blood glucose (2h-ppg) and glycosylated hemoglobin (HbA1c) in the case group were respectively (4.75±0.30) mmol/L, (5.69±0.74) mmol/L, (5.15±0.28)%, control group were respectively (5.01±0.30) mmol/L, (6.15±0.70) mmol/L, (5.68±0.33)%. The difference was statistically between the two groups (t=-4.631、-3.019、-8.020, P<0.05 or 0.01). The treatment compliance rate, gestational hypertension, hyperhydramnios, cesarean section and macrosomia rate in the case group were respectively 93.2% (41/44), 6.8% (3/44), 11.4% (5/44), 13.6% (6/44), 2.3% (1/44), control group were respectively 81.4% (35/43), 23.3% (10/43), 30.2% (13/43), 32.6% (14/43), 14.0% (6/43), the difference was statistically between the two groups (U=570.000, χ2=4.398-5.775, P<0.01 or 0.05).@*Conclusion@#Teach-back method is methodis a good health method and to reduce glucose level and improve Compliance of therapy. It is worthy of promotion.
ABSTRACT
Objective To explore the effects of teach-back on health education for patients′gestational diabetes mellitus. Methods A total of 90 pregnant women with gestational diabetes mellitus from obstetrics outpatient were recruited and randomly assigned to either case or control group. The case and control groups received the same treatment and health education, the only difference was teach-back method in the case group,to compare blood glucose, compliance and outcome of pregnancy. Results After the intervention, fasting blood glucose (FPG), 2h postprandial blood glucose (2h- ppg) and glycosylated hemoglobin (HbA1c) in the case group were respectively (4.75 ± 0.30) mmol/L, (5.69 ± 0.74) mmol/L, (5.15±0.28)%,control group were respectively (5.01±0.30) mmol/L, (6.15±0.70) mmol/L, (5.68± 0.33)% . The difference was statistically between the two groups (t=-4.631、-3.019、-8.020, P<0.05 or 0.01). The treatment compliance rate, gestational hypertension, hyperhydramnios, cesarean section and macrosomia rate in the case group were respectively 93.2% (41/44), 6.8% (3/44), 11.4% (5/44), 13.6% (6/44), 2.3% (1/44),control group were respectively 81.4% (35/43), 23.3% (10/43), 30.2% (13/43), 32.6% (14/43), 14.0% (6/43),the difference was statistically between the two groups ( U=570.000, χ2 =4.398-5.775, P<0.01 or 0.05). Conclusion Teach-back method is methodis a good health method and to reduce glucose level and improve Compliance of therapy. It is worthy of promotion.
ABSTRACT
Objective To establish the baseline data about gross α and gross β radioactivity in local foods through a preliminary investigation in Urumqi City.Methods The edible parts of six types of foods, including cereals, vegetables, fruit, nuts, meat and dairy food, were pretreated and sampled.MPC 9604 low background o and gross β measuring instrument was used for determination of gross α and gross β radioactivity.Results The natural gross ot and gross β radioactivity in the cereal, vegetables, fruits, nut, meat, dairy food were 0.88-10.80 and 22.20-148.67 in cereals, 1.17-24.24 and 21.41-318.84 in vegetables, 1.44-4.89 and 43.90-112.67 in fruits, 17.49-43.72 and 287.81-747.40 in nut, 3.04 -19.77 and 41.55-164.51 in meat, and 2.07-2.94 and 44.07-59.02 Bq/kg in milk, respectively.Conclusions There are some differences in the gross natural radioactivity between Urumqi and the other provinces and cities due to possible regional differences.In order to further ascertain baseline of natural radioactivity in food in Urumqi, larger sample sizes and more diverse food types are needed for purposes of dynamic monitoring.
ABSTRACT
Objective To observe gene different expression of unfolded protein response signaling pathway in human osteoblasts under the excessive fluoride ,and explore the role of endoplasmic reticulum stress in fluorosis .Methods Human osteoblasts were cultured with fluoride ,intervening for 24 h .Cell viability and apoptosis were inspected by MTS assay and flow cytometer respective‐ly .The UPR signaling pathway was examined by real time PCR array ,and protein expressions were detected by Western blot .Re‐sults T he cell survival rates w ere (100 .678 5 ± 2 .830 3 )% ,(105 .393 4 ± 2 .538 4 )% ,(106 .125 7 ± 2 .048 3 )% ,(77 .977 3 ± 2 .544 3)% (P<0 .05) ,(30 .237 7 ± 0 .632 73)% (P<0 .05) treated with sodium fluoride at the concentration 0 ,5 ,10 ,20 ,40 ,80 mg/L respectively .Apoptosis rate inspected by flow cytometer was 4 .8% in 5 mg/L group ,13 .8% in 10 mg/L group ,37 .0% in 20 mg/L group ,58 .9% in 40 mg/L group ,63 .2% in 80 mg/L group (P<0 .05) .Only 1 gene was down regulated and 14 genes were up regulated .Western blot analysis showed BIP ,ATF4 ,CHOP and IRE1 both showed their protein expression gradually up regula‐ted with fluorine dose .XBP1 expression gradually increased in NaF 5-20 mg/L ,and its expression decreased at 40 and 80 mg/L . Conclusion Sodium fluoride can cause osteoblasts endoplasmic reticulum stress pathway through PTEN and IRE1 pathway ,and at high concentrations can cause apoptosis of osteoblast .
ABSTRACT
Objective To observe the effects of liver-discharging and stomach-harmonizing therapy on quality of life in senile patients with reflux esophagitis and to evaluate the therapeutic effect of traditional Chinese medicine (TCM) on chronic diseases. Methods Sixty patients with senile reflux esophagitis selected from in-patients and out-patients of Henan Province Hospital of TCM from March 2012 to October 2013 were randomly divided into experimental group and control group(each,30 patients). The experimental group was treated with Xiaoyao powder (its ingredients could be added or subtracted according to the patient's individual situation)combined with omeprazole and domperidone,while in the control group,only western drugs,omeprazole and domperidone were applied. The therapies in both groups lasting for 8 weeks constituted one therapeutic course. The MOS 36-item short form healthy survey(SF-36)was used to evaluate the degree of improvement of patients,quality of life,and clinical effects and adverse drug reaction were observed. Results The total scores of SF-36,physical and mental health scores of both groups were increased significantly,and the degree of elevation in scores in the experimental group was markedly higher than that in the control group(total scores of SF-36:124.2±11.5 vs. 117.1±10.9,physical health scores:67.9±5.3 vs. 62.9±6.2,mental health scores:56.1±6.7 vs. 55.0±6.6,all P<0.05). The total effective rate of experimental group was much superior to that of control group(96.7%vs. 80.0%,P<0.05). No obvious adverse reactions happened in the two groups. Conclusion Liver-discharging and stomach-harmonizing therapy can improve the quality of life in aged patients with reflux esophagitis.
ABSTRACT
0.05). However, incidences of VRS paining grade, nausea and vomiting in Z-type stainless steel stent group were significantly higher than Ni-Ti alloy mesh stent group (P 0.05). All patients in both groups did not have general toxicity and hypersensitivity reaction, and they had normal cell component, number and form of hematopoieticsystem. CONCLUSION: Both Z-type stainless steel stent and Ni-Ti alloy mesh stent are suitable for alleviative treatment of advanced esophageal cancer; however, side effects induced by Ni-Ti alloy mesh stent is less than by Z-type stainless steel stent in an early postoperative stage.