1.
Chinese Journal of Clinical Pharmacology and Therapeutics
;
(12): 1159-1166, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-1014959
ABSTRACT
Liver cancer is one of the most dangerous malignant tumors in China. It has the characteristics of high mortality and occult onset. At present, the treatment of liver cancer is mainly targeted drugs, surgery and chemoradiotherapy, which is prone to high recurrence rate and strong drug resistance. In this paper, glutamine metabolism as the breakthrough point, the glutamine metabolism enzymes and related genes related to liver cancer are reviewed, in order to provide an open new idea for the pathogenesis and drug treatment of liver cancer.