ABSTRACT
Objective To explore the clinical effect of pituitrin and oxytocin in laparoscopy myomectomy of intramural fibroids.Methods Sixty patients received laparoscopy myomectomy of intramural fibroids during October 2015-December 2016 were selected and divided into two groups with 30 cases in each.We applied injections of pituitrin 6IU + 10ml normal saline to treatment group while 20U oxytocin + 10ml normal saline to control group so as to compare their blood pressure change and other situations based on medication.Results Compared with control group,the time of operation and amount of bleeding during operation in treatment group reduced obviously(98.13 ± 5.07min vs 110.83 ± 8.03min,t =-7.324,P =0.000).The hemoglobin changed before and after operation (67.50 ±10.24ml vs 97.83 ± 16.10ml,t =-8.705,P =0.000).15min after medication during operation,the systolic pressure in treatment group increased obviously,which was higher than that in control group(150.77 ±:5.57mmHg vs 142.03 ± 5.21mmHg,t =6.273,P =0.000).Conclusion The application of pituitrin to laparoscopy myomeetomy of intramural fibroids was better hemostatic effect than oxytoein,but it may geuerate temporary elevation of blood pressure,so the clinical application should combine with patients' individual situation.
ABSTRACT
Object To study the chemical constituents of a new species belonging to genus Tinospora (Menispermaceae)— the Tinospora hainanensis H S Lo et Z X Li Methods Isolation and purification were carried out on silica gel column, identified by physico chemical properties and structurally elucidated by spectral analysis Results 4 non alkaloids were obtained They were 24 epi makisterone A (Ⅰ), octacosanoic acid (Ⅱ), octacosyl alcohol (Ⅲ) and hexacosyl alcohol (Ⅳ) Conclusion All of the 4 compounds were obtained from this plant for the first time, and compounds Ⅰ, Ⅱ and Ⅳ were obtained from genus Tinospora for the first time